HIV-1 Nef employs two distinct mechanisms to modulate Lck subcellular localization and TCR induced actin remodeling.

par Claudia Haller, Susanne Rauch, Oliver T Fackler
Publié 2007

HIV-1 Vpu Blocks Recycling and Biosynthetic Transport of the Intrinsic Immunity Factor CD317/Tetherin To Overcome the Virion Release Restriction

par Sarah Schmidt, Joëlle V. Fritz, Julia Bitzegeio, Oliver T. Fackler, Oliver T. Keppler
Publié 2011

Association with PAK2 Enables Functional Interactions of Lentiviral Nef Proteins with the Exocyst Complex

par Andrea Imle, Libin Abraham, Nikolaos Tsopoulidis, Bernard Hoflack, Kalle Saksela, Oliver T. Fackler
Publié 2015

Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef.

par Sebastian Breuer, Simone I Schievink, Antje Schulte, Wulf Blankenfeldt, Oliver T Fackler, Matthias Geyer
Publié 2011

The identification of a small molecule compound that reduces HIV-1 Nef-mediated viral infectivity enhancement.

par Nopporn Chutiwitoonchai, Masateru Hiyoshi, Philip Mwimanzi, Takamasa Ueno, Akio Adachi, Hirotaka Ode, Hironori Sato, Oliver T Fackler, Seiji Okada, Shinya Suzu
Publié 2011

GPCR-induced calcium transients trigger nuclear actin assembly for chromatin dynamics

par Ying Wang, Alice Sherrard, Bing Zhao, Michael Melak, Jonathan Trautwein, Eva-Maria Kleinschnitz, Nikolaos Tsopoulidis, Oliver T. Fackler, Carsten Schwan, Robert Grosse
Publié 2019

Flavivirus Infection Uncouples Translation Suppression from Cellular Stress Responses

par Hanna Roth, Vera Magg, Fabian Uch, Pascal Mutz, Philipp Klein, Katharina Haneke, Volker Lohmann, Ralf Bartenschlager, Oliver T. Fackler, Nicolas Locker, Georg Stoecklin, Alessia Ruggieri
Publié 2017

Erratum for Roth et al., “Flavivirus Infection Uncouples Translation Suppression from Cellular Stress Responses”

par Hanna Roth, Vera Magg, Fabian Uch, Pascal Mutz, Philipp Klein, Katharina Haneke, Volker Lohmann, Ralf Bartenschlager, Oliver T. Fackler, Nicolas Locker, Georg Stoecklin, Alessia Ruggieri
Publié 2017

Experimental and computational analyses reveal that environmental restrictions shape HIV-1 spread in 3D cultures

par Andrea Imle, Peter Kumberger, Nikolas D. Schnellbächer, Jana Fehr, Paola Carrillo-Bustamante, Janez Ales, Philip Schmidt, Christian Ritter, William J. Godinez, Barbara Müller, Karl Rohr, Fred A. Hamprecht, Ulrich S. Schwarz, Frederik Graw, Oliver T. Fackler
Publié 2019

Human tetherin exerts strong selection pressure on the HIV-1 group N Vpu protein.

par Daniel Sauter, Daniel Unterweger, Michael Vogl, Shariq M Usmani, Anke Heigele, Silvia F Kluge, Elisabeth Hermkes, Markus Moll, Edward Barker, Martine Peeters, Gerald H Learn, Frederic Bibollet-Ruche, Joëlle V Fritz, Oliver T Fackler, Beatrice H Hahn, Frank Kirchhoff
Publié 2012