A novel small compound SH-2251 suppresses Th2 cell-dependent airway inflammation through selective modulation of chromatin status at the Il5 gene locus.

por Junpei Suzuki, Makoto Kuwahara, Soichi Tofukuji, Masashi Imamura, Fuminori Kato, Toshinori Nakayama, Osamu Ohara, Masakatsu Yamashita
Publicado 2013

Essential Role of STAT3 Signaling in Hair Follicle Homeostasis

por Kosuke Miyauchi, Sewon Ki, Masao Ukai, Masao Ukai, Yoshie Suzuki, Kentaro Inoue, Kentaro Inoue, Wataru Suda, Wataru Suda, Takeshi Matsui, Yoshihiro Ito, Kenya Honda, Kenya Honda, Haruhiko Koseki, Haruhiko Koseki, Osamu Ohara, Osamu Ohara, Reiko J. Tanaka, Mariko Okada-Hatakeyama, Mariko Okada-Hatakeyama, Mariko Okada-Hatakeyama, Masato Kubo, Masato Kubo
Publicado 2021

Influenza virus infection expands the breadth of antibody responses through IL-4 signalling in B cells

por Kosuke Miyauchi, Yu Adachi, Keisuke Tonouchi, Taiki Yajima, Yasuyo Harada, Hidehiro Fukuyama, Senka Deno, Yoichiro Iwakura, Akihiko Yoshimura, Hideki Hasegawa, Katsuyuki Yugi, Shin-ichiro Fujii, Osamu Ohara, Yoshimasa Takahashi, Masato Kubo
Publicado 2021

SCD2-mediated monounsaturated fatty acid metabolism regulates cGAS-STING-dependent type I IFN responses in CD4+ T cells

por Toshio Kanno, Takahiro Nakajima, Satoru Yokoyama, Hikari K. Asou, Shigemi Sasamoto, Yasuhiro Kamii, Koji Hayashizaki, Yasuo Ouchi, Taishi Onodera, Yoshimasa Takahashi, Kazutaka Ikeda, Yoshinori Hasegawa, Yuki Kinjo, Osamu Ohara, Toshinori Nakayama, Yusuke Endo
Publicado 2021

Bach2–Batf interactions control Th2-type immune response by regulating the IL-4 amplification loop

por Makoto Kuwahara, Wataru Ise, Mizuki Ochi, Junpei Suzuki, Kohei Kometani, Saho Maruyama, Maya Izumoto, Akira Matsumoto, Nobuaki Takemori, Ayako Takemori, Kenta Shinoda, Toshinori Nakayama, Osamu Ohara, Masaki Yasukawa, Tatsuya Sawasaki, Tomohiro Kurosaki, Masakatsu Yamashita
Publicado 2016

Generation of orthotopically functional salivary gland from embryonic stem cells

por Junichi Tanaka, Miho Ogawa, Hironori Hojo, Yusuke Kawashima, Yo Mabuchi, Kenji Hata, Shiro Nakamura, Rika Yasuhara, Koki Takamatsu, Tarou Irié, Toshiyuki Fukada, Takayoshi Sakai, Tomio Inoue, Riko Nishimura, Osamu Ohara, Ichiro Saito, Shinsuke Ohba, Takashi Tsuji, Kenji Mishima
Publicado 2018

Mast cells play role in wound healing through the ZnT2/GPR39/IL-6 axis

por Keigo Nishida, Aiko Hasegawa, Satoru Yamasaki, Ryota Uchida, Wakana Ohashi, Yosuke Kurashima, Jun Kunisawa, Shunsuke Kimura, Toshihiko Iwanaga, Hiroshi Watarai, Koji Hase, Hideki Ogura, Manabu Nakayama, Jun-ichi Kashiwakura, Yoshimichi Okayama, Masato Kubo, Osamu Ohara, Hiroshi Kiyono, Haruhiko Koseki, Masaaki Murakami, Toshio Hirano
Publicado 2019