Natural selection in the evolution of SARS-CoV-2 in bats created a generalist virus and highly capable human pathogen.

por Oscar A MacLean, Spyros Lytras, Steven Weaver, Joshua B Singer, Maciej F Boni, Philippe Lemey, Sergei L Kosakovsky Pond, David L Robertson
Publicado 2021

Adaptive Evolution of RH5 in Ape <italic toggle="yes">Plasmodium</italic> species of the <italic toggle="yes">Laverania</italic> Subgenus

por Lindsey J. Plenderleith, Weimin Liu, Oscar A. MacLean, Yingying Li, Dorothy E. Loy, Sesh A. Sundararaman, Frederic Bibollet-Ruche, Gerald H. Learn, Beatrice H. Hahn, Paul M. Sharp
Publicado 2018

Reply to Forni et al., “Multiple Selected Changes May Modulate the Molecular Interaction between <italic toggle="yes">Laverania</italic> RH5 and Primate Basigin”

por Lindsey J. Plenderleith, Weimin Liu, Oscar A. MacLean, Yingying Li, Dorothy E. Loy, Sesh A. Sundararaman, Frederic Bibollet-Ruche, Gerald H. Learn, Beatrice H. Hahn, Paul M. Sharp
Publicado 2018

In vitro selection of Remdesivir resistance suggests evolutionary predictability of SARS-CoV-2.

por Agnieszka M Szemiel, Andres Merits, Richard J Orton, Oscar A MacLean, Rute Maria Pinto, Arthur Wickenhagen, Gauthier Lieber, Matthew L Turnbull, Sainan Wang, Wilhelm Furnon, Nicolas M Suarez, Daniel Mair, Ana da Silva Filipe, Brian J Willett, Sam J Wilson, Arvind H Patel, Emma C Thomson, Massimo Palmarini, Alain Kohl, Meredith E Stewart
Publicado 2021