NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway

por Iva Hafner-Bratkovič, Petra Sušjan, Duško Lainšček, Ana Tapia-Abellán, Kosta Cerović, Lucija Kadunc, Diego Angosto-Bazarra, Pablo Pelegrin, Roman Jerala
Publicado 2018

Extracellular NLRP3 inflammasome particles are internalized by human coronary artery smooth muscle cells and induce pro-atherogenic effects

por Susanne Gaul, Karen Marie Schaeffer, Lena Opitz, Christina Maeder, Alexander Kogel, Luisa Uhlmann, Hermann Kalwa, Ulf Wagner, Jan Haas, Amirhossein Behzadi, Pablo Pelegrin, Jes-Niels Boeckel, Ulrich Laufs
Publicado 2021

Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins

por Sylwia D. Tyrkalska, Sergio Candel, Diego Angosto, Victoria Gómez-Abellán, Fátima Martín-Sánchez, Diana García-Moreno, Rubén Zapata-Pérez, Álvaro Sánchez-Ferrer, María P. Sepulcre, Pablo Pelegrín, Victoriano Mulero
Publicado 2016

SCN4B acts as a metastasis-suppressor gene preventing hyperactivation of cell migration in breast cancer

por Emeline Bon, Virginie Driffort, Frédéric Gradek, Carlos Martinez-Caceres, Monique Anchelin, Pablo Pelegrin, Maria-Luisa Cayuela, Séverine Marionneau-Lambot, Thibauld Oullier, Roseline Guibon, Gaëlle Fromont, Jorge L. Gutierrez-Pajares, Isabelle Domingo, Eric Piver, Alain Moreau, Julien Burlaud-Gaillard, Philippe G. Frank, Stéphan Chevalier, Pierre Besson, Sébastien Roger
Publicado 2016

P2X7 receptor induces mitochondrial failure in monocytes and compromises NLRP3 inflammasome activation during sepsis

por Juan José Martínez-García, Helios Martínez-Banaclocha, Diego Angosto-Bazarra, Carlos de Torre-Minguela, Alberto Baroja-Mazo, Cristina Alarcón-Vila, Laura Martínez-Alarcón, Joaquín Amores-Iniesta, Fátima Martín-Sánchez, Giovanni A. Ercole, Carlos M. Martínez, Ada González-Lisorge, José Fernández-Pacheco, Piedad Martínez-Gil, Sahil Adriouch, Friedrich Koch-Nolte, Juan Luján, Francisco Acosta-Villegas, Pascual Parrilla, Carlos García-Palenciano, Pablo Pelegrin
Publicado 2019