Distinct Cytokine Profiles Correlate with Disease Severity and Outcome in Longitudinal Studies of Acute Hepatitis B Virus and Hepatitis D Virus Infection in Chimpanzees

por Ronald E. Engle, Davide De Battista, Emily J. Danoff, Hanh Nguyen, Zhaochun Chen, Paolo Lusso, Robert H. Purcell, Patrizia Farci
Publicado 2020

Functional Anatomy of the Trimer Apex Reveals Key Hydrophobic Constraints That Maintain the HIV-1 Envelope Spike in a Closed State

por Peng Zhang, Alice L. Kwon, Christina Guzzo, Qingbo Liu, Hana Schmeisser, Huiyi Miao, Yin Lin, Raffaello Cimbro, Jinghe Huang, Mark Connors, Stephen D. Schmidt, Michael A. Dolan, Anthony A. Armstrong, Paolo Lusso
Publicado 2021

Structural Constraints at the Trimer Apex Stabilize the HIV-1 Envelope in a Closed, Antibody-Protected Conformation

por Christina Guzzo, Peng Zhang, Qingbo Liu, Alice L. Kwon, Ferzan Uddin, Alexandra I. Wells, Hana Schmeisser, Raffaello Cimbro, Jinghe Huang, Nicole Doria-Rose, Stephen D. Schmidt, Michael A. Dolan, Mark Connors, John R. Mascola, Paolo Lusso
Publicado 2018

Improvement of antibody functionality by structure-guided paratope engraftment

por Qingbo Liu, Yen-Ting Lai, Peng Zhang, Mark K. Louder, Amarendra Pegu, Reda Rawi, Mangaiarkarasi Asokan, Xuejun Chen, Chen-Hsiang Shen, Gwo-Yu Chuang, Eun Sung Yang, Huiyi Miao, Yuge Wang, Anthony S. Fauci, Peter D. Kwong, John R. Mascola, Paolo Lusso
Publicado 2019