Poloxamer-based binary hydrogels for delivering tramadol hydrochloride: sol-gel transition studies, dissolution-release kinetics, in vitro toxicity, and pharmacological evaluation

por dos Santos ACM, Akkari ACS, Ferreira IRS, Maruyama CR, Pascoli M, Guilherme VA, de Paula E, Fraceto LF, de Lima R, Melo PS, de Araujo DR
Publicado 2015