Tyrosine kinase inhibitors induce down-regulation of c-Kit by targeting the ATP pocket.

por Diane D'allard, Julie Gay, Clotilde Descarpentries, Emilie Frisan, Kevin Adam, Frederique Verdier, Célia Floquet, Patrice Dubreuil, Catherine Lacombe, Michaela Fontenay, Patrick Mayeux, Olivier Kosmider
Publicado 2013

Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT.

por Patrice Dubreuil, Sébastien Letard, Marco Ciufolini, Laurent Gros, Martine Humbert, Nathalie Castéran, Laurence Borge, Bérengère Hajem, Anne Lermet, Wolfgang Sippl, Edwige Voisset, Michel Arock, Christian Auclair, Phillip S Leventhal, Colin D Mansfield, Alain Moussy, Olivier Hermine
Publicado 2009

Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology

por Kahina Hammam, Magali Saez-Ayala, Etienne Rebuffet, Laurent Gros, Sophie Lopez, Berengere Hajem, Martine Humbert, Emilie Baudelet, Stephane Audebert, Stephane Betzi, Adrien Lugari, Sebastien Combes, Sebastien Letard, Nathalie Casteran, Colin Mansfield, Alain Moussy, Paulo De Sepulveda, Xavier Morelli, Patrice Dubreuil
Publicado 2017

Case-control cohort study of patients' perceptions of disability in mastocytosis.

por Olivier Hermine, Olivier Lortholary, Phillip S Leventhal, Adeline Catteau, Frédérique Soppelsa, Cedric Baude, Annick Cohen-Akenine, Fabienne Palmérini, Katia Hanssens, Ying Yang, Hagay Sobol, Sylvie Fraytag, David Ghez, Felipe Suarez, Stéphane Barete, Philippe Casassus, Beatrice Sans, Michel Arock, Jean Pierre Kinet, Patrice Dubreuil, Alain Moussy
Publicado 2008

Phenotypic and genotypic characteristics of mastocytosis according to the age of onset.

por Fanny Lanternier, Annick Cohen-Akenine, Fabienne Palmerini, Frédéric Feger, Ying Yang, Yael Zermati, Stéphane Barète, Beatrix Sans, Cédric Baude, David Ghez, Felipe Suarez, Richard Delarue, Philippe Casassus, Christine Bodemer, Adeline Catteau, Frédérique Soppelsa, Katia Hanssens, Michel Arock, Hagay Sobol, Sylvie Fraitag, Danièle Canioni, Alain Moussy, Jean Marie Launay, Patrice Dubreuil, Olivier Hermine, Olivier Lortholary, AFIRMM network
Publicado 2008