Landscape of transcriptomic interactions between breast cancer and its microenvironment

por Natalie S. Fox, Syed Haider, Adrian L. Harris, Paul C. Boutros
Publicado 2019

mRNA levels in control rat liver display strain-specific, hereditary, and AHR-dependent components.

por Paul C Boutros, Ivy D Moffat, Allan B Okey, Raimo Pohjanvirta
Publicado 2011

Divergent mutational processes distinguish hypoxic and normoxic tumours

por Vinayak Bhandari, Constance H. Li, Robert G. Bristow, Paul C. Boutros, PCAWG Consortium
Publicado 2020

Quantifying the influence of mutation detection on tumour subclonal reconstruction

por Lydia Y. Liu, Vinayak Bhandari, Adriana Salcedo, Shadrielle M. G. Espiritu, Quaid D. Morris, Thomas Kislinger, Paul C. Boutros
Publicado 2020

PDGFRα+ stromal adipocyte progenitors transition into epithelial cells during lobulo-alveologenesis in the murine mammary gland

por Purna A. Joshi, Paul D. Waterhouse, Katayoon Kasaian, Hui Fang, Olga Gulyaeva, Hei Sook Sul, Paul C. Boutros, Rama Khokha
Publicado 2019

Sex differences in oncogenic mutational processes

por Constance H. Li, Stephenie D. Prokopec, Ren X. Sun, Fouad Yousif, Nathaniel Schmitz, PCAWG Tumour Subtypes and Clinical Translation, Paul C. Boutros, PCAWG Consortium
Publicado 2020

Integrative pathway enrichment analysis of multivariate omics data

por Marta Paczkowska, Jonathan Barenboim, Nardnisa Sintupisut, Natalie S. Fox, Helen Zhu, Diala Abd-Rabbo, Miles W. Mee, Paul C. Boutros, PCAWG Drivers and Functional Interpretation Working Group, Jüri Reimand, PCAWG Consortium
Publicado 2020

Use of Sequenom sample ID Plus® SNP genotyping in identification of FFPE tumor samples.

por Jessica K Miller, Nicholas Buchner, Lee Timms, Shirley Tam, Xuemei Luo, Andrew M K Brown, Danielle Pasternack, Robert G Bristow, Michael Fraser, Paul C Boutros, John D McPherson
Publicado 2014

MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability

por Dharmendra Dingar, William B. Tu, Diana Resetca, Corey Lourenco, Aaliya Tamachi, Jason De Melo, Kathleen E. Houlahan, Manpreet Kalkat, Pak-Kei Chan, Paul C. Boutros, Brian Raught, Linda Z. Penn
Publicado 2018

Targeted proteomics identifies liquid-biopsy signatures for extracapsular prostate cancer

por Yunee Kim, Jouhyun Jeon, Salvador Mejia, Cindy Q Yao, Vladimir Ignatchenko, Julius O Nyalwidhe, Anthony O Gramolini, Raymond S Lance, Dean A Troyer, Richard R Drake, Paul C Boutros, O. John Semmes, Thomas Kislinger
Publicado 2016

The telomere length landscape of prostate cancer

por Julie Livingstone, Yu-Jia Shiah, Takafumi N. Yamaguchi, Lawrence E. Heisler, Vincent Huang, Robert Lesurf, Tsumugi Gebo, Benjamin Carlin, Stefan Eng, Erik Drysdale, Jeffrey Green, Theodorus van der Kwast, Robert G. Bristow, Michael Fraser, Paul C. Boutros
Publicado 2021

Molecular stratification of early breast cancer identifies drug targets to drive stratified medicine

por Jane Bayani, Cindy Q. Yao, Mary Anne Quintayo, Fu Yan, Syed Haider, Alister D’Costa, Cassandra L. Brookes, Cornelis J. H. van de Velde, Annette Hasenburg, Dirk G. Kieback, Christos Markopoulos, Luc Dirix, Caroline Seynaeve, Daniel Rea, Paul C. Boutros, John M. S. Bartlett
Publicado 2017

Transcriptional perturbation of protein arginine methyltransferase-5 exhibits MTAP-selective oncosuppression

por Sara Busacca, Qi Zhang, Annabel Sharkey, Alan G. Dawson, David A. Moore, David A. Waller, Apostolos Nakas, Carolyn Jones, Kelvin Cain, Jin-li Luo, Adriana Salcedo, Iris Chiara Salaroglio, Chiara Riganti, John Le Quesne, Tom John, Paul C. Boutros, Shu-Dong Zhang, Dean A. Fennell
Publicado 2021

Comparative survival analysis of multiparametric tests—when molecular tests disagree—A TEAM Pathology study

por John M. S. Bartlett, Jane Bayani, Elizabeth Kornaga, Keying Xu, Greg R. Pond, Tammy Piper, Elizabeth Mallon, Cindy Q. Yao, Paul C. Boutros, Annette Hasenburg, J. A. Dunn, Christos Markopoulos, Luc Dirix, Caroline Seynaeve, Cornelis J. H. van de Velde, Robert C. Stein, Daniel Rea
Publicado 2021

Mitochondrial mutations drive prostate cancer aggression

por Julia F. Hopkins, Veronica Y. Sabelnykova, Joachim Weischenfeldt, Ronald Simon, Jennifer A. Aguiar, Rached Alkallas, Lawrence E. Heisler, Junyan Zhang, John D. Watson, Melvin L. K. Chua, Michael Fraser, Francesco Favero, Chris Lawerenz, Christoph Plass, Guido Sauter, John D. McPherson, Theodorus van der Kwast, Jan Korbel, Thorsten Schlomm, Robert G. Bristow, Paul C. Boutros
Publicado 2017

3p Arm Loss and Survival in Head and Neck Cancer: An Analysis of TCGA Dataset

por Hugh Andrew Jinwook Kim, Mushfiq Hassan Shaikh, Mark Lee, Peter Y. F. Zeng, Alana Sorgini, Temitope Akintola, Xiaoxiao Deng, Laura Jarycki, Halema Khan, Danielle MacNeil, Mohammed Imran Khan, Adrian Mendez, John Yoo, Kevin Fung, Pencilla Lang, David A. Palma, Krupal Patel, Joe S. Mymryk, John W. Barrett, Paul C. Boutros, Luc G. T. Morris, Anthony C. Nichols
Publicado 2021

Mapping genomic and transcriptomic alterations spatially in epithelial cells adjacent to human breast carcinoma

por Moustafa Abdalla, Danh Tran-Thanh, Juan Moreno, Vladimir Iakovlev, Ranju Nair, Nisha Kanwar, Mohamed Abdalla, Jennifer P. Y. Lee, Jennifer Yin Yee Kwan, Thomas R. Cawthorn, Keisha Warren, Nona Arneson, Dong-Yu Wang, Natalie S. Fox, Bruce J. Youngson, Naomi A. Miller, Alexandra M. Easson, David McCready, Wey L. Leong, Paul C. Boutros, Susan J. Done
Publicado 2017

The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact

por Lisanne F. van Dessel, Job van Riet, Minke Smits, Yanyun Zhu, Paul Hamberg, Michiel S. van der Heijden, Andries M. Bergman, Inge M. van Oort, Ronald de Wit, Emile E. Voest, Neeltje Steeghs, Takafumi N. Yamaguchi, Julie Livingstone, Paul C. Boutros, John W. M. Martens, Stefan Sleijfer, Edwin Cuppen, Wilbert Zwart, Harmen J. G. van de Werken, Niven Mehra, Martijn P. Lolkema
Publicado 2019

Pathway-based subnetworks enable cross-disease biomarker discovery

por Syed Haider, Cindy Q. Yao, Vicky S. Sabine, Michal Grzadkowski, Vincent Stimper, Maud H. W. Starmans, Jianxin Wang, Francis Nguyen, Nathalie C. Moon, Xihui Lin, Camilla Drake, Cheryl A. Crozier, Cassandra L. Brookes, Cornelis J. H. van de Velde, Annette Hasenburg, Dirk G. Kieback, Christos J. Markopoulos, Luc Y. Dirix, Caroline Seynaeve, Daniel W. Rea, Arek Kasprzyk, Philippe Lambin, Pietro Lio’, John M. S. Bartlett, Paul C. Boutros
Publicado 2018

A Canadian Study of Cisplatin Metabolomics and Nephrotoxicity (ACCENT): A Clinical Research Protocol

por Anshika Jain, Ryan Huang, Jasmine Lee, Natasha Jawa, Yong Jin Lim, Mike Guron, Sharon Abish, Paul C. Boutros, Michael Brudno, Bruce Carleton, Geoffrey D. E. Cuvelier, Lakshman Gunaratnam, Cheryl Ho, Khosrow Adeli, Sara Kuruvilla, Giles Lajoie, Geoffrey Liu, Paul C. Nathan, Shahrad Rod Rassekh, Michael Rieder, Sushrut S. Waikar, Stephen A. Welch, Matthew A. Weir, Eric Winquist, David S. Wishart, Alexandra P. Zorzi, Tom Blydt-Hansen, Michael Zappitelli, Bradley Urquhart
Publicado 2021