Bordetella adenylate cyclase toxin mobilizes its beta2 integrin receptor into lipid rafts to accomplish translocation across target cell membrane in two steps.

por Ladislav Bumba, Jiri Masin, Radovan Fiser, Peter Sebo
Publicado 2010

<italic toggle="yes">Bordetella</italic> Adenylate Cyclase Toxin Inhibits Monocyte-to-Macrophage Transition and Dedifferentiates Human Alveolar Macrophages into Monocyte-like Cells

por Jawid Nazir Ahmad, Jana Holubova, Oldrich Benada, Olga Kofronova, Ludek Stehlik, Martina Vasakova, Peter Sebo
Publicado 2019

Selective Enhancement of the Cell-Permeabilizing Activity of Adenylate Cyclase Toxin Does Not Increase Virulence of <i>Bordetella pertussis</i>

por Jana Holubova, Attila Juhasz, Jiri Masin, Ondrej Stanek, David Jurnecka, Adriana Osickova, Peter Sebo, Radim Osicka
Publicado 2021

Structural Basis of Ca²⁺-Dependent Self-Processing Activity of Repeat-in-Toxin Proteins

por Vojtech Kuban, Pavel Macek, Jozef Hritz, Katerina Nechvatalova, Katerina Nedbalcova, Martin Faldyna, Peter Sebo, Lukas Zidek, Ladislav Bumba
Publicado 2020

A Mutation Upstream of the <italic toggle="yes">rplN-rpsD</italic> Ribosomal Operon Downregulates <named-content content-type="genus-species">Bordetella pertussis</named-content> V...

por Jakub Novák, David Jurnečka, Irena Linhartová, Jana Holubová, Ondřej Staněk, Daniel Štipl, Ana Dienstbier, Branislav Večerek, Nayara Azevedo, Jan Provazník, Vladimír Beneš, Peter Šebo
Publicado 2020

Different roles of conserved tyrosine residues of the acylated domains in folding and activity of RTX toxins

por Anna Lepesheva, Adriana Osickova, Jana Holubova, David Jurnecka, Sarka Knoblochova, Carlos Espinosa-Vinals, Ladislav Bumba, Karolina Skopova, Radovan Fiser, Radim Osicka, Peter Sebo, Jiri Masin
Publicado 2021

Calcium influx rescues adenylate cyclase-hemolysin from rapid cell membrane removal and enables phagocyte permeabilization by toxin pores.

por Radovan Fiser, Jiri Masin, Ladislav Bumba, Eva Pospisilova, Catherine Fayolle, Marek Basler, Lenka Sadilkova, Irena Adkins, Jana Kamanova, Jan Cerny, Ivo Konopasek, Radim Osicka, Claude Leclerc, Peter Sebo
Publicado 2012