A scalable online tool for quantitative social network assessment reveals potentially modifiable social environmental risks

por Amar Dhand, Charles C. White, Catherine Johnson, Zongqi Xia, Philip L. De Jager
Publicado 2018

Unified AI framework to uncover deep interrelationships between gene expression and Alzheimer’s disease neuropathologies

por Nicasia Beebe-Wang, Safiye Celik, Ethan Weinberger, Pascal Sturmfels, Philip L. De Jager, Sara Mostafavi, Su-In Lee
Publicado 2021

Characterization of mitochondrial DNA quantity and quality in the human aged and Alzheimer’s disease brain

por Hans-Ulrich Klein, Caroline Trumpff, Hyun-Sik Yang, Annie J. Lee, Martin Picard, David A. Bennett, Philip L. De Jager
Publicado 2021

Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer’s disease

por Andrew S. P. Lim, Hans-Ulrich Klein, Lei Yu, Lori B. Chibnik, Sanam Ali, Jishu Xu, David A. Bennett, Philip L. De Jager
Publicado 2017

Serum metabolomic biomarkers of perceptual speed in cognitively normal and mildly impaired subjects with fasting state stratification

por Kamil Borkowski, Ameer Y. Taha, Theresa L. Pedersen, Philip L. De Jager, David A. Bennett, Matthias Arnold, Rima Kaddurah-Daouk, John W. Newman
Publicado 2021

Neuropathological correlates and genetic architecture of microglial activation in elderly human brain

por Daniel Felsky, Tina Roostaei, Kwangsik Nho, Shannon L. Risacher, Elizabeth M. Bradshaw, Vlad Petyuk, Julie A. Schneider, Andrew Saykin, David A. Bennett, Philip L. De Jager
Publicado 2019

Retraction: 24-Hour Rhythms of DNA Methylation and Their Relation with Rhythms of RNA Expression in the Human Dorsolateral Prefrontal Cortex

por Andrew S. P. Lim, Gyan P. Srivastava, Lei Yu, Lori B. Chibnik, Jishu Xu, Aron S. Buchman, Julie A. Schneider, Amanda J. Myers, David A. Bennett, Philip L. De Jager, the Editors
Publicado 2021

Cortical proteins may provide motor resilience in older adults

por Aron S. Buchman, Lei Yu, Shahram Oveisgharan, Vladislav A. Petyuk, Shinya Tasaki, Chris Gaiteri, Robert S. Wilson, Francine Grodstein, Julie A. Schneider, Hans-Ulrich Klein, Philip L. De Jager, David A. Bennett
Publicado 2021

Retraction: 24-Hour Rhythms of DNA Methylation and Their Relation with Rhythms of RNA Expression in the Human Dorsolateral Prefrontal Cortex.

por Andrew S P Lim, Gyan P Srivastava, Lei Yu, Lori B Chibnik, Jishu Xu, Aron S Buchman, Julie A Schneider, Amanda J Myers, David A Bennett, Philip L De Jager, PLOS Genetics Editors
Publicado 2021

Molecular estimation of neurodegeneration pseudotime in older brains

por Sumit Mukherjee, Laura Heath, Christoph Preuss, Suman Jayadev, Gwenn A. Garden, Anna K. Greenwood, Solveig K. Sieberts, Philip L. De Jager, Nilüfer Ertekin-Taner, Gregory W. Carter, Lara M. Mangravite, Benjamin A. Logsdon
Publicado 2020

Author Correction: Molecular estimation of neurodegeneration pseudotime in older brains

por Sumit Mukherjee, Laura Heath, Christoph Preuss, Suman Jayadev, Gwenn A. Garden, Anna K. Greenwood, Solveig K. Sieberts, Philip L. De Jager, Nilüfer Ertekin-Taner, Gregory W. Carter, Lara M. Mangravite, Benjamin A. Logsdon
Publicado 2020

Two genetic variants explain the association of European ancestry with multiple sclerosis risk in African-Americans

por Nathan Nakatsuka, Nick Patterson, Nikolaos A. Patsopoulos, Nicolas Altemose, Arti Tandon, Ashley H. Beecham, Jacob L. McCauley, Noriko Isobe, Stephen Hauser, Philip L. De Jager, David A. Hafler, Jorge R. Oksenberg, David Reich
Publicado 2020

Author Correction: Nuclei multiplexing with barcoded antibodies for single-nucleus genomics

por Jellert T. Gaublomme, Bo Li, Cristin McCabe, Abigail Knecht, Yiming Yang, Eugene Drokhlyansky, Nicholas Van Wittenberghe, Julia Waldman, Danielle Dionne, Lan Nguyen, Philip L. De Jager, Bertrand Yeung, Xinfang Zhao, Naomi Habib, Orit Rozenblatt-Rosen, Aviv Regev
Publicado 2020

Nuclei multiplexing with barcoded antibodies for single-nucleus genomics

por Jellert T. Gaublomme, Bo Li, Cristin McCabe, Abigail Knecht, Yiming Yang, Eugene Drokhlyansky, Nicholas Van Wittenberghe, Julia Waldman, Danielle Dionne, Lan Nguyen, Philip L. De Jager, Bertrand Yeung, Xinfang Zhao, Naomi Habib, Orit Rozenblatt-Rosen, Aviv Regev
Publicado 2019

A machine learning approach to brain epigenetic analysis reveals kinases associated with Alzheimer’s disease

por Yanting Huang, Xiaobo Sun, Huige Jiang, Shaojun Yu, Chloe Robins, Matthew J. Armstrong, Ronghua Li, Zhen Mei, Xiaochuan Shi, Ekaterina Sergeevna Gerasimov, Philip L. De Jager, David A. Bennett, Aliza P. Wingo, Peng Jin, Thomas S. Wingo, Zhaohui S. Qin
Publicado 2021

A transcriptomic atlas of aged human microglia

por Marta Olah, Ellis Patrick, Alexandra-Chloe Villani, Jishu Xu, Charles C. White, Katie J. Ryan, Paul Piehowski, Alifiya Kapasi, Parham Nejad, Maria Cimpean, Sarah Connor, Christina J. Yung, Michael Frangieh, Allison McHenry, Wassim Elyaman, Vlad Petyuk, Julie A. Schneider, David A. Bennett, Philip L. De Jager, Elizabeth M. Bradshaw
Publicado 2018

Atlas of RNA editing events affecting protein expression in aged and Alzheimer’s disease human brain tissue

por Yiyi Ma, Eric B. Dammer, Daniel Felsky, Duc M. Duong, Hans-Ulrich Klein, Charles C. White, Maotian Zhou, Benjamin A. Logsdon, Cristin McCabe, Jishu Xu, Minghui Wang, Thomas S. Wingo, James J. Lah, Bin Zhang, Julie Schneider, Mariet Allen, Xue Wang, Nilüfer Ertekin-Taner, Nicholas T. Seyfried, Allan I. Levey, David A. Bennett, Philip L. De Jager
Publicado 2021

Alterations of the human gut microbiome in multiple sclerosis

por Sushrut Jangi, Roopali Gandhi, Laura M. Cox, Ning Li, Felipe von Glehn, Raymond Yan, Bonny Patel, Maria Antonietta Mazzola, Shirong Liu, Bonnie L. Glanz, Sandra Cook, Stephanie Tankou, Fiona Stuart, Kirsy Melo, Parham Nejad, Kathleen Smith, Begüm D. Topçuolu, James Holden, Pia Kivisäkk, Tanuja Chitnis, Philip L. De Jager, Francisco J. Quintana, Georg K. Gerber, Lynn Bry, Howard L. Weiner
Publicado 2016

A meta-analysis of epigenome-wide association studies in Alzheimer’s disease highlights novel differentially methylated loci across cortex

por Rebecca G. Smith, Ehsan Pishva, Gemma Shireby, Adam R. Smith, Janou A. Y. Roubroeks, Eilis Hannon, Gregory Wheildon, Diego Mastroeni, Gilles Gasparoni, Matthias Riemenschneider, Armin Giese, Andrew J. Sharp, Leonard Schalkwyk, Vahram Haroutunian, Wolfgang Viechtbauer, Daniel L. A. van den Hove, Michael Weedon, Danielle Brokaw, Paul T. Francis, Alan J. Thomas, Seth Love, Kevin Morgan, Jörn Walter, Paul D. Coleman, David A. Bennett, Philip L. De Jager, Jonathan Mill, Katie Lunnon
Publicado 2021

Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease

por Marta Olah, Vilas Menon, Naomi Habib, Mariko F. Taga, Yiyi Ma, Christina J. Yung, Maria Cimpean, Anthony Khairallah, Guillermo Coronas-Samano, Roman Sankowski, Dominic Grün, Alexandra A. Kroshilina, Danielle Dionne, Rani A. Sarkis, Garth R. Cosgrove, Jeffrey Helgager, Jeffrey A. Golden, Page B. Pennell, Marco Prinz, Jean Paul G. Vonsattel, Andrew F. Teich, Julie A. Schneider, David A. Bennett, Aviv Regev, Wassim Elyaman, Elizabeth M. Bradshaw, Philip L. De Jager
Publicado 2020