Immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy to eradicate colorectal tumors

by Xiaopin Duan, Christina Chan, Wenbo Han, Nining Guo, Ralph R. Weichselbaum, Wenbin Lin
Published 2019

Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy

by Chunbai He, Xiaopin Duan, Nining Guo, Christina Chan, Christopher Poon, Ralph R. Weichselbaum, Wenbin Lin
Published 2016

Nanoscale metal-organic frameworks enhance radiotherapy to potentiate checkpoint blockade immunotherapy

by Kaiyuan Ni, Guangxu Lan, Christina Chan, Bryan Quigley, Kuangda Lu, Theint Aung, Nining Guo, Patrick La Riviere, Ralph R. Weichselbaum, Wenbin Lin
Published 2018

p50 mono-ubiquitination and interaction with BARD1 regulates cell cycle progression and maintains genome stability

by Longtao Wu, Clayton D. Crawley, Andrea Garofalo, Jackie W. Nichols, Paige-Ashley Campbell, Galina F. Khramtsova, Olufunmilayo I. Olopade, Ralph R. Weichselbaum, Bakhtiar Yamini
Published 2020

CDK1 is up-regulated by temozolomide in an NF-κB dependent manner in glioblastoma

by David J. Voce, Giovanna M. Bernal, Kirk E. Cahill, Longtao Wu, Nassir Mansour, Clayton D. Crawley, Paige-Ashley S. Campbell, Ainhoa Arina, Ralph R. Weichselbaum, Bakhtiar Yamini
Published 2021

Host STING-dependent MDSC mobilization drives extrinsic radiation resistance

by Hua Liang, Liufu Deng, Yuzhu Hou, Xiangjiao Meng, Xiaona Huang, Enyu Rao, Wenxin Zheng, Helena Mauceri, Matthias Mack, Meng Xu, Yang-Xin Fu, Ralph R. Weichselbaum
Published 2017

Network modeling identifies molecular functions targeted by miR-204 to suppress head and neck tumor metastasis.

by Younghee Lee, Xinan Yang, Yong Huang, Hanli Fan, Qingbei Zhang, Youngfei Wu, Jianrong Li, Rifat Hasina, Chao Cheng, Mark W Lingen, Mark B Gerstein, Ralph R Weichselbaum, H Rosie Xing, Yves A Lussier
Published 2010

Adenoviral transduction of human acid sphingomyelinase into neo-angiogenic endothelium radiosensitizes tumor cure.

by Branka Stancevic, Nira Varda-Bloom, Jin Cheng, John D Fuller, Jimmy A Rotolo, Mónica García-Barros, Regina Feldman, Shyam Rao, Ralph R Weichselbaum, Dror Harats, Adriana Haimovitz-Friedman, Zvi Fuks, Michel Sadelain, Richard Kolesnick
Published 2013

Tumor-reprogrammed resident T cells resist radiation to control tumors

by Ainhoa Arina, Michael Beckett, Christian Fernandez, Wenxin Zheng, Sean Pitroda, Steven J. Chmura, Jason J. Luke, Martin Forde, Yuzhu Hou, Byron Burnette, Helena Mauceri, Israel Lowy, Tasha Sims, Nikolai Khodarev, Yang-Xin Fu, Ralph R. Weichselbaum
Published 2019

DNA repair biomarkers XPF and phospho-MAPKAP kinase 2 correlate with clinical outcome in advanced head and neck cancer.

by Tanguy Y Seiwert, XiaoZhe Wang, Jana Heitmann, Vivian Villegas-Bergazzi, Kam Sprott, Stephen Finn, Esther O'Regan, Allan D Farrow, Ralph R Weichselbaum, Mark W Lingen, Ezra E W Cohen, Kerstin Stenson, David T Weaver, Everett E Vokes
Published 2014

CDKN2A loss-of-function predicts immunotherapy resistance in non-small cell lung cancer

by Stanley I. Gutiontov, William Tyler Turchan, Liam F. Spurr, Sherin J. Rouhani, Carolina Soto Chervin, George Steinhardt, Angela M. Lager, Pankhuri Wanjari, Renuka Malik, Philip P. Connell, Steven J. Chmura, Aditya Juloori, Philip C. Hoffman, Mark K. Ferguson, Jessica S. Donington, Jyoti D. Patel, Everett E. Vokes, Ralph R. Weichselbaum, Christine M. Bestvina, Jeremy P. Segal, Sean P. Pitroda
Published 2021

Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis

by Sean P. Pitroda, Nikolai N. Khodarev, Lei Huang, Abhineet Uppal, Sean C. Wightman, Sabha Ganai, Nora Joseph, Jason Pitt, Miguel Brown, Martin Forde, Kathy Mangold, Lai Xue, Christopher Weber, Jeremy P. Segal, Sabah Kadri, Melinda E. Stack, Sajid Khan, Philip Paty, Karen Kaul, Jorge Andrade, Kevin P. White, Mark Talamonti, Mitchell C. Posner, Samuel Hellman, Ralph R. Weichselbaum
Published 2018

Author Correction: Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis

by Sean P. Pitroda, Nikolai N. Khodarev, Lei Huang, Abhineet Uppal, Sean C. Wightman, Sabha Ganai, Nora Joseph, Jason Pitt, Miguel Brown, Martin Forde, Kathy Mangold, Lai Xue, Christopher Weber, Jeremy P. Segal, Sabah Kadri, Melinda E. Stack, Sajid Khan, Philip Paty, Karen Kaul, Jorge Andrade, Kevin P. White, Mark Talamonti, Mitchell C. Posner, Samuel Hellman, Ralph R. Weichselbaum
Published 2018

Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity

by Sangman M. Kim, Jennifer R. DeFazio, Sanjiv K. Hyoju, Kishan Sangani, Robert Keskey, Monika A. Krezalek, Nikolai N. Khodarev, Naseer Sangwan, Scott Christley, Katharine G. Harris, Ankit Malik, Alexander Zaborin, Romain Bouziat, Diana R. Ranoa, Mara Wiegerinck, Jordan D. Ernest, Baddr A. Shakhsheer, Irma D. Fleming, Ralph R. Weichselbaum, Dionysios A. Antonopoulos, Jack A. Gilbert, Luis B. Barreiro, Olga Zaborina, Bana Jabri, John C. Alverdy
Published 2020

Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells

by Demet Candas-Green, Bowen Xie, Jie Huang, Ming Fan, Aijun Wang, Cheikh Menaa, Yanhong Zhang, Lu Zhang, Di Jing, Soheila Azghadi, Weibing Zhou, Lin Liu, Nian Jiang, Tao Li, Tianyi Gao, Colleen Sweeney, Rulong Shen, Tzu-yin Lin, Chong-xian Pan, Omer M. Ozpiskin, Gayle Woloschak, David J. Grdina, Andrew T. Vaughan, Ji Ming Wang, Shuli Xia, Arta M. Monjazeb, William J. Murphy, Lun-Quan Sun, Hong-Wu Chen, Kit S. Lam, Ralph R. Weichselbaum, Jian Jian Li
Published 2020