Stimulation of CRISPR-mediated homology-directed repair by an engineered RAD18 variant

por Tarun S. Nambiar, Pierre Billon, Giacomo Diedenhofen, Samuel B. Hayward, Angelo Taglialatela, Kunheng Cai, Jen-Wei Huang, Giuseppe Leuzzi, Raquel Cuella-Martin, Andrew Palacios, Anuj Gupta, Dieter Egli, Alberto Ciccia
Publicado 2019

The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity

por Jordan R. Becker, Raquel Cuella-Martin, Marco Barazas, Rui Liu, Catarina Oliveira, Antony W. Oliver, Kirstin Bilham, Abbey B. Holt, Andrew N. Blackford, Jörg Heierhorst, Jos Jonkers, Sven Rottenberg, J. Ross Chapman
Publicado 2018

MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage

por Jen-Wei Huang, Ananya Acharya, Angelo Taglialatela, Tarun S. Nambiar, Raquel Cuella-Martin, Giuseppe Leuzzi, Samuel B. Hayward, Sarah A. Joseph, Gregory J. Brunette, Roopesh Anand, Rajesh K. Soni, Nathan L. Clark, Kara A. Bernstein, Petr Cejka, Alberto Ciccia
Publicado 2020