A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression

por Chrysanthi Taxiarchi, Andrea Beaghton, Nayomi Illansinhage Don, Kyros Kyrou, Matthew Gribble, Dammy Shittu, Scott P. Collins, Chase L. Beisel, Roberto Galizi, Andrea Crisanti
Publicado 2021

Resistance to a CRISPR-based gene drive at an evolutionarily conserved site is revealed by mimicking genotype fixation.

por Silke Fuchs, William T Garrood, Anna Beber, Andrew Hammond, Roberto Galizi, Matthew Gribble, Giulia Morselli, Tin-Yu J Hui, Katie Willis, Nace Kranjc, Austin Burt, Andrea Crisanti, Tony Nolan
Publicado 2021

The Potential for a Released Autosomal X-Shredder Becoming a Driving-Y Chromosome and Invasively Suppressing Wild Populations of Malaria Mosquitoes

por Yehonatan Alcalay, Silke Fuchs, Roberto Galizi, Federica Bernardini, Roya Elaine Haghighat-Khah, Douglas B. Rusch, Jeffrey R. Adrion, Matthew W. Hahn, Matthew W. Hahn, Pablo Tortosa, Rachel Rotenberry, Philippos Aris Papathanos
Publicado 2021