The plant-derived glucocorticoid receptor agonist Endiandrin A acts as co-stimulator of colonic epithelial sodium channels (ENaC) via SGK-1 and MAPKs.

par Dana Kuntzsch, Theresa Bergann, Petra Dames, Anja Fromm, Michael Fromm, Rohan A Davis, Matthias F Melzig, Joerg D Schulzke
Publié 2012

The serrulatane diterpenoid natural products RAD288 and RAD289 stimulate properties of olfactory ensheathing cells useful for neural repair therapies

par Mo Chen, Marie-Laure Vial, Johana Tello Velasquez, Jenny A. K. Ekberg, Rohan A. Davis, James A. St John
Publié 2018

A combinatorial approach for the discovery of cytochrome P450 2D6 inhibitors from nature

par Johannes Hochleitner, Muhammad Akram, Martina Ueberall, Rohan A. Davis, Birgit Waltenberger, Hermann Stuppner, Sonja Sturm, Florian Ueberall, Johanna M. Gostner, Daniela Schuster
Publié 2017