Optogenetic control of nuclear protein export

par Dominik Niopek, Pierre Wehler, Julia Roensch, Roland Eils, Barbara Di Ventura
Publié 2016

Decision-tree based model analysis for efficient identification of parameter relations leading to different signaling states.

par Yvonne Koch, Thomas Wolf, Peter K Sorger, Roland Eils, Benedikt Brors
Publié 2013

Role of the ESCRT Complexes in Telomere Biology

par Anna K. Dieckmann, Vera Babin, Yaniv Harari, Roland Eils, Rainer König, Brian Luke, Martin Kupiec
Publié 2016

Multi-parametric analysis and modeling of relationships between mitochondrial morphology and apoptosis.

par Yara Reis, Marti Bernardo-Faura, Daniela Richter, Thomas Wolf, Benedikt Brors, Anne Hamacher-Brady, Roland Eils, Nathan R Brady
Publié 2012

Familial Cancer Variant Prioritization Pipeline version 2 (FCVPPv2) applied to a papillary thyroid cancer family

par Abhishek Kumar, Obul Reddy Bandapalli, Nagarajan Paramasivam, Sara Giangiobbe, Chiara Diquigiovanni, Elena Bonora, Roland Eils, Matthias Schlesner, Kari Hemminki, Asta Försti
Publié 2018

MYC/MIZ1-dependent gene repression inversely coordinates the circadian clock with cell cycle and proliferation

par Anton Shostak, Bianca Ruppert, Nati Ha, Philipp Bruns, Umut H. Toprak, ICGC MMML-Seq Project, Roland Eils, Matthias Schlesner, Axel Diernfellner, Michael Brunner
Publié 2016

miR-17-5p regulates endocytic trafficking through targeting TBC1D2/Armus.

par Andrius Serva, Bettina Knapp, Yueh-Tso Tsai, Christoph Claas, Tautvydas Lisauskas, Petr Matula, Nathalie Harder, Lars Kaderali, Karl Rohr, Holger Erfle, Roland Eils, Vania Braga, Vytaute Starkuviene
Publié 2012

Single-cell analysis of patient-derived PDAC organoids reveals cell state heterogeneity and a conserved developmental hierarchy

par Teresa G. Krieger, Solange Le Blanc, Julia Jabs, Foo Wei Ten, Naveed Ishaque, Katharina Jechow, Olivia Debnath, Carl-Stephan Leonhardt, Anamika Giri, Roland Eils, Oliver Strobel, Christian Conrad
Publié 2021

Coverage bias and sensitivity of variant calling for four whole-genome sequencing technologies.

par Nora Rieber, Marc Zapatka, Bärbel Lasitschka, David Jones, Paul Northcott, Barbara Hutter, Natalie Jäger, Marcel Kool, Michael Taylor, Peter Lichter, Stefan Pfister, Stephan Wolf, Benedikt Brors, Roland Eils
Publié 2013

Cell segmentation-free inference of cell types from in situ transcriptomics data

par Jeongbin Park, Wonyl Choi, Sebastian Tiesmeyer, Brian Long, Lars E. Borm, Emma Garren, Thuc Nghi Nguyen, Bosiljka Tasic, Simone Codeluppi, Tobias Graf, Matthias Schlesner, Oliver Stegle, Roland Eils, Naveed Ishaque
Publié 2021

Author Correction: Cell segmentation-free inference of cell types from in situ transcriptomics data

par Jeongbin Park, Wonyl Choi, Sebastian Tiesmeyer, Brian Long, Lars E. Borm, Emma Garren, Thuc Nghi Nguyen, Bosiljka Tasic, Simone Codeluppi, Tobias Graf, Matthias Schlesner, Oliver Stegle, Roland Eils, Naveed Ishaque
Publié 2021

Putative second hit rare genetic variants in families with seemingly GBA-associated Parkinson’s disease

par Muhammad Aslam, Nirosiya Kandasamy, Anwar Ullah, Nagarajan Paramasivam, Mehmet Ali Öztürk, Saima Naureen, Abida Arshad, Mazhar Badshah, Kafaitullah Khan, Muhammad Wajid, Rashda Abbasi, Muhammad Ilyas, Roland Eils, Matthias Schlesner, Rebecca C. Wade, Nafees Ahmad, Jakob von Engelhardt
Publié 2021

Phenocopy--a strategy to qualify chemical compounds during hit-to-lead and/or lead optimization.

par Patrick Baum, Ramona Schmid, Carina Ittrich, Werner Rust, Katrin Fundel-Clemens, Susanne Siewert, Martin Baur, Lisa Mara, Lore Gruenbaum, Armin Heckel, Roland Eils, Roland E Kontermann, Gerald J Roth, Florian Gantner, Andreas Schnapp, John E Park, Andreas Weith, Karsten Quast, Detlev Mennerich
Publié 2010

Characterizing protein interactions employing a genome-wide siRNA cellular phenotyping screen.

par Apichat Suratanee, Martin H Schaefer, Matthew J Betts, Zita Soons, Heiko Mannsperger, Nathalie Harder, Marcus Oswald, Markus Gipp, Ellen Ramminger, Guillermo Marcus, Reinhard Männer, Karl Rohr, Erich Wanker, Robert B Russell, Robert B Russell, Miguel A Andrade-Navarro, Roland Eils, Rainer König
Publié 2014

Genomic footprints of activated telomere maintenance mechanisms in cancer

par Lina Sieverling, Chen Hong, Sandra D. Koser, Philip Ginsbach, Kortine Kleinheinz, Barbara Hutter, Delia M. Braun, Isidro Cortés-Ciriano, Ruibin Xi, Rolf Kabbe, Peter J. Park, Roland Eils, Matthias Schlesner, PCAWG-Structural Variation Working Group, Benedikt Brors, Karsten Rippe, David T. W. Jones, Lars Feuerbach, PCAWG Consortium
Publié 2020

Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands

par Florian Haller, Matthias Bieg, Rainer Will, Cindy Körner, Dieter Weichenhan, Alexander Bott, Naveed Ishaque, Pavlo Lutsik, Evgeny A. Moskalev, Sarina K. Mueller, Marion Bähr, Angelika Woerner, Birgit Kaiser, Claudia Scherl, Marlen Haderlein, Kortine Kleinheinz, Rainer Fietkau, Heinrich Iro, Roland Eils, Arndt Hartmann, Christoph Plass, Stefan Wiemann, Abbas Agaimy
Publié 2019

Framework for quality assessment of whole genome cancer sequences

par Justin P. Whalley, Ivo Buchhalter, Esther Rheinbay, Keiran M. Raine, Miranda D. Stobbe, Kortine Kleinheinz, Johannes Werner, Sergi Beltran, Marta Gut, Daniel Hübschmann, Barbara Hutter, Dimitri Livitz, Marc D. Perry, Mara Rosenberg, Gordon Saksena, Jean-Rémi Trotta, Roland Eils, Daniela S. Gerhard, Peter J. Campbell, Matthias Schlesner, Ivo G. Gut
Publié 2020

Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype

par Yonghe Wu, Michael Fletcher, Zuguang Gu, Qi Wang, Barbara Costa, Anna Bertoni, Ka-Hou Man, Magdalena Schlotter, Jörg Felsberg, Jasmin Mangei, Martje Barbus, Ann-Christin Gaupel, Wei Wang, Tobias Weiss, Roland Eils, Michael Weller, Haikun Liu, Guido Reifenberger, Andrey Korshunov, Peter Angel, Peter Lichter, Carl Herrmann, Bernhard Radlwimmer
Publié 2020

Whole genome sequencing puts forward hypotheses on metastasis evolution and therapy in colorectal cancer

par Naveed Ishaque, Mohammed L. Abba, Christine Hauser, Nitin Patil, Nagarajan Paramasivam, Daniel Huebschmann, Jörg Hendrik Leupold, Gnana Prakash Balasubramanian, Kortine Kleinheinz, Umut H. Toprak, Barbara Hutter, Axel Benner, Anna Shavinskaya, Chan Zhou, Zuguang Gu, Jules Kerssemakers, Alexander Marx, Marcin Moniuszko, Miroslaw Kozlowski, Joanna Reszec, Jacek Niklinski, Jürgen Eils, Matthias Schlesner, Roland Eils, Benedikt Brors, Heike Allgayer
Publié 2018

Genomic features of renal cell carcinoma with venous tumor thrombus

par Gregor Warsow, Daniel Hübschmann, Kortine Kleinheinz, Cathleen Nientiedt, Martina Heller, Laura Van Coile, Yanis Tolstov, Lukas Trennheuser, Kathrin Wieczorek, Carine Pecqueux, Claudia Gasch, Timur Kuru, Joanne Nyarangi-Dix, Gencay Hatiboglu, Dogu Teber, Sven Perner, Albrecht Stenzinger, Wilfried Roth, Boris Hadaschik, Sascha Pahernik, Dirk Jäger, Carsten Grüllich, Anette Duensing, Roland Eils, Matthias Schlesner, Holger Sültmann, Markus Hohenfellner, Stefan Duensing
Publié 2018