Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase

por Blake E. Smith, Stephen L. Wang, Saul Jaime-Figueroa, Alicia Harbin, Jing Wang, Brian D. Hamman, Craig M. Crews
Publicado 2019

Mutant-selective degradation by BRAF-targeting PROTACs

por Shanique Alabi, Saul Jaime-Figueroa, Zhan Yao, Yijun Gao, John Hines, Kusal T. G. Samarasinghe, Lea Vogt, Neal Rosen, Craig M. Crews
Publicado 2021