Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma

par Kenneth Verstraete, Frank Peelman, Harald Braun, Juan Lopez, Dries Van Rompaey, Ann Dansercoer, Isabel Vandenberghe, Kris Pauwels, Jan Tavernier, Bart N. Lambrecht, Hamida Hammad, Hans De Winter, Rudi Beyaert, Guy Lippens, Savvas N. Savvides
Publié 2017

Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha

par Srinath Govindarajan, Djoere Gaublomme, Renée Van der Cruyssen, Eveline Verheugen, Sofie Van Gassen, Yvan Saeys, Simon Tavernier, Takao Iwawaki, Yehudi Bloch, Savvas. N. Savvides, Bart N. Lambrecht, Sophie Janssens, Dirk Elewaut, Michael B. Drennan
Publié 2018

Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF

par Jan Felix, Eaazhisai Kandiah, Steven De Munck, Yehudi Bloch, Gydo C.P. van Zundert, Kris Pauwels, Ann Dansercoer, Katka Novanska, Randy J. Read, Alexandre M.J.J. Bonvin, Bjorn Vergauwen, Kenneth Verstraete, Irina Gutsche, Savvas N. Savvides
Publié 2016

Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis

par Karolina Slowicka, Inmaculada Serramito-Gómez, Emilio Boada-Romero, Arne Martens, Mozes Sze, Ioanna Petta, Hanna K. Vikkula, Riet De Rycke, Eef Parthoens, Saskia Lippens, Savvas N. Savvides, Andy Wullaert, Lars Vereecke, Felipe X. Pimentel-Muiños, Geert van Loo
Publié 2019

Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation

par Yves Dondelinger, Tom Delanghe, Dario Priem, Meghan A. Wynosky-Dolfi, Daniel Sorobetea, Diego Rojas-Rivera, Piero Giansanti, Ria Roelandt, Julia Gropengiesser, Klaus Ruckdeschel, Savvas N. Savvides, Albert J. R. Heck, Peter Vandenabeele, Igor E. Brodsky, Mathieu J. M. Bertrand
Publié 2019

Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding

par Klaas Yperman, Anna C. Papageorgiou, Romain Merceron, Steven De Munck, Yehudi Bloch, Dominique Eeckhout, Qihang Jiang, Pieter Tack, Rosa Grigoryan, Thomas Evangelidis, Jelle Van Leene, Laszlo Vincze, Peter Vandenabeele, Frank Vanhaecke, Martin Potocký, Geert De Jaeger, Savvas N. Savvides, Konstantinos Tripsianes, Roman Pleskot, Daniel Van Damme
Publié 2021