Linkage of genetic drivers and strain-specific germline variants confound mouse cancer genome analyses

por Sebastian Mueller, Sebastian Lange, Katharina A. N. Collins, Stefan Krebs, Helmut Blum, Günter Schneider, Lena Rad, Dieter Saur, Roland Rad
Publicado 2020

Attenuated and protease-profile modified sendai virus vectors as a new tool for virotherapy of solid tumors.

por Martina Zimmermann, Sorin Armeanu-Ebinger, Sascha Bossow, Johanna Lampe, Irina Smirnow, Andrea Schenk, Sebastian Lange, Thomas S Weiss, Wolfgang Neubert, Ulrich M Lauer, Michael Bitzer
Publicado 2014

Functional analysis of peripheral and intratumoral neoantigen-specific TCRs identified in a patient with melanoma

por Melanie Boxberg, Katja Steiger, Wilko Weichert, Roland Rad, Kai Yu, Sebastian Lange, Thomas Engleitner, Huan Lan, Eva Bräunlein, Gaia Lupoli, Franziska Füchsl, Esam T Abualrous, Niklas de Andrade Krätzig, Dario Gosmann, Lukas Wietbrock, Stefan Audehm, Manuel Effenberger, Yinshui Chang, Cigdem Atay, Florian Bassermann, Dirk H Busch, Christian Freund, Iris Antes, Angela M Krackhardt
Publicado 2021

Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice

por Roman Maresch, Sebastian Mueller, Christian Veltkamp, Rupert Öllinger, Mathias Friedrich, Irina Heid, Katja Steiger, Julia Weber, Thomas Engleitner, Maxim Barenboim, Sabine Klein, Sandra Louzada, Ruby Banerjee, Alexander Strong, Teresa Stauber, Nina Gross, Ulf Geumann, Sebastian Lange, Marc Ringelhan, Ignacio Varela, Kristian Unger, Fengtang Yang, Roland M. Schmid, George S. Vassiliou, Rickmer Braren, Günter Schneider, Mathias Heikenwalder, Allan Bradley, Dieter Saur, Roland Rad
Publicado 2016

Single cell polarity in liquid phase facilitates tumour metastasis

por Anna Lorentzen, Paul F. Becker, Jan Kosla, Massimo Saini, Kathrin Weidele, Paolo Ronchi, Corinna Klein, Monika J. Wolf, Felix Geist, Bastian Seubert, Marc Ringelhan, Daniela Mihic-Probst, Knud Esser, Marko Roblek, Felix Kuehne, Gaia Bianco, Tracy O’Connor, Quentin Müller, Kathleen Schuck, Sebastian Lange, Daniel Hartmann, Saskia Spaich, Olaf Groß, Jochen Utikal, Sebastian Haferkamp, Martin R. Sprick, Amruta Damle-Vartak, Alexander Hapfelmeier, Norbert Hüser, Ulrike Protzer, Andreas Trumpp, Dieter Saur, Nachiket Vartak, Christoph A. Klein, Bernhard Polzer, Lubor Borsig, Mathias Heikenwalder
Publicado 2018

MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically

por Enkhtsetseg Munkhbaatar, Michelle Dietzen, Deepti Agrawal, Martina Anton, Moritz Jesinghaus, Melanie Boxberg, Nicole Pfarr, Pidassa Bidola, Sebastian Uhrig, Ulrike Höckendorf, Anna-Lena Meinhardt, Adam Wahida, Irina Heid, Rickmer Braren, Ritu Mishra, Arne Warth, Thomas Muley, Patrina S. P. Poh, Xin Wang, Stefan Fröhling, Katja Steiger, Julia Slotta-Huspenina, Martijn van Griensven, Franz Pfeiffer, Sebastian Lange, Roland Rad, Magda Spella, Georgios T. Stathopoulos, Jürgen Ruland, Florian Bassermann, Wilko Weichert, Andreas Strasser, Caterina Branca, Mathias Heikenwalder, Charles Swanton, Nicholas McGranahan, Philipp J. Jost
Publicado 2020