USP11 controls R-loops by regulating senataxin proteostasis

por Mateusz Jurga, Arwa A. Abugable, Alastair S. H. Goldman, Sherif F. El-Khamisy
Publicado 2021

Integrative microRNA and gene expression analysis identifies new epigenetically regulated microRNAs mediating taxane resistance in ovarian cancer

por Mohamed K. Hassan, Amr A. Waly, Waheba Elsayed, Sarah Keshk, Walaa Ramadan Allam, Sherif F. El-khamisy
Publicado 2021

Typhoid toxin exhausts the RPA response to DNA replication stress driving senescence and Salmonella infection

por Angela E. M. Ibler, Mohamed ElGhazaly, Kathryn L. Naylor, Natalia A. Bulgakova, Sherif F. El-Khamisy, Daniel Humphreys
Publicado 2019

Hypoxia-induced SETX links replication stress with the unfolded protein response

por Shaliny Ramachandran, Tiffany S. Ma, Jon Griffin, Natalie Ng, Iosifina P. Foskolou, Ming-Shih Hwang, Pedro Victori, Wei-Chen Cheng, Francesca M. Buffa, Katarzyna B. Leszczynska, Sherif F. El-Khamisy, Natalia Gromak, Ester M. Hammond
Publicado 2021

TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts

por John Fielden, Katherine Wiseman, Ignacio Torrecilla, Shudong Li, Samuel Hume, Shih-Chieh Chiang, Annamaria Ruggiano, Abhay Narayan Singh, Raimundo Freire, Sylvana Hassanieh, Enric Domingo, Iolanda Vendrell, Roman Fischer, Benedikt M. Kessler, Timothy S. Maughan, Sherif F. El-Khamisy, Kristijan Ramadan
Publicado 2020

SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits

por Guillaume M. Hautbergue, Lydia M. Castelli, Laura Ferraiuolo, Alvaro Sanchez-Martinez, Johnathan Cooper-Knock, Adrian Higginbottom, Ya-Hui Lin, Claudia S. Bauer, Jennifer E. Dodd, Monika A. Myszczynska, Sarah M. Alam, Pierre Garneret, Jayanth S. Chandran, Evangelia Karyka, Matthew J. Stopford, Emma F. Smith, Janine Kirby, Kathrin Meyer, Brian K. Kaspar, Adrian M. Isaacs, Sherif F. El-Khamisy, Kurt J. De Vos, Ke Ning, Mimoun Azzouz, Alexander J. Whitworth, Pamela J. Shaw
Publicado 2017