Microfluidic Isolation of Circulating Tumor Cell Clusters by Size and Asymmetry

par Sam H. Au, Jon Edd, Amy E. Stoddard, Keith H. K. Wong, Fabio Fachin, Shyamala Maheswaran, Daniel A. Haber, Shannon L. Stott, Ravi Kapur, Mehmet Toner
Publié 2017

Preservative solution that stabilizes erythrocyte morphology and leukocyte viability under ambient conditions

par Rebecca D. Sandlin, Keith H. K. Wong, Leo Boneschansker, Thomas R. Carey, Kathleen L. Miller, Gregory Rose, Daniel A. Haber, Shyamala Maheswaran, Daniel Irimia, Shannon L. Stott, Mehmet Toner
Publié 2017

SETD1A protects from senescence through regulation of the mitotic gene expression program

par Ken Tajima, Satoru Matsuda, Toshifumi Yae, Benjamin J. Drapkin, Robert Morris, Myriam Boukhali, Kira Niederhoffer, Valentine Comaills, Taronish Dubash, Linda Nieman, Hongshan Guo, Neelima K. C. Magnus, Nick Dyson, Toshihiro Shioda, Wilhelm Haas, Daniel A. Haber, Shyamala Maheswaran
Publié 2019

HIF1A signaling selectively supports proliferation of breast cancer in the brain

par Richard Y. Ebright, Marcus A. Zachariah, Douglas S. Micalizzi, Ben S. Wittner, Kira L. Niederhoffer, Linda T. Nieman, Brian Chirn, Devon F. Wiley, Benjamin Wesley, Brian Shaw, Edwin Nieblas-Bedolla, Lian Atlas, Annamaria Szabolcs, Anthony J. Iafrate, Mehmet Toner, David T. Ting, Priscilla K. Brastianos, Daniel A. Haber, Shyamala Maheswaran
Publié 2020

Monolithic Chip for High-throughput Blood Cell Depletion to Sort Rare Circulating Tumor Cells

par Fabio Fachin, Philipp Spuhler, Joseph M. Martel-Foley, Jon F. Edd, Thomas A. Barber, John Walsh, Murat Karabacak, Vincent Pai, Melissa Yu, Kyle Smith, Henry Hwang, Jennifer Yang, Sahil Shah, Ruby Yarmush, Lecia V. Sequist, Shannon L. Stott, Shyamala Maheswaran, Daniel A. Haber, Ravi Kapur, Mehmet Toner
Publié 2017

Pancreatic circulating tumor cell profiling identifies LIN28B as a metastasis driver and drug target

par Joseph W. Franses, Julia Philipp, Pavlos Missios, Irun Bhan, Ann Liu, Chittampalli Yashaswini, Eric Tai, Huili Zhu, Matteo Ligorio, Benjamin Nicholson, Elizabeth M. Tassoni, Niyati Desai, Anupriya S. Kulkarni, Annamaria Szabolcs, Theodore S. Hong, Andrew S. Liss, Carlos Fernandez-del Castillo, David P. Ryan, Shyamala Maheswaran, Daniel A. Haber, George Q. Daley, David T. Ting
Publié 2020

Whole blood stabilization for the microfluidic isolation and molecular characterization of circulating tumor cells

par Keith H. K. Wong, Shannon N. Tessier, David T. Miyamoto, Kathleen L. Miller, Lauren D. Bookstaver, Thomas R. Carey, Cleo J. Stannard, Vishal Thapar, Eric C. Tai, Kevin D. Vo, Erin S. Emmons, Haley M. Pleskow, Rebecca D. Sandlin, Lecia V. Sequist, David T. Ting, Daniel A. Haber, Shyamala Maheswaran, Shannon L. Stott, Mehmet Toner
Publié 2017

Expression of β-globin by cancer cells promotes cell survival during blood-borne dissemination

par Yu Zheng, David T. Miyamoto, Ben S. Wittner, James P. Sullivan, Nicola Aceto, Nicole Vincent Jordan, Min Yu, Nezihi Murat Karabacak, Valentine Comaills, Robert Morris, Rushil Desai, Niyati Desai, Erin Emmons, John D. Milner, Richard J. Lee, Chin-Lee Wu, Lecia V. Sequist, Wilhelm Haas, David T. Ting, Mehmet Toner, Sridhar Ramaswamy, Shyamala Maheswaran, Daniel A. Haber
Publié 2017