The pro-regenerative effects of hyperIL6 in drug-induced liver injury are unexpectedly due to competitive inhibition of IL11 signaling

par Jinrui Dong, Sivakumar Viswanathan, Eleonora Adami, Sebastian Schafer, Fathima F Kuthubudeen, Anissa A Widjaja, Stuart A Cook
Publié 2021

Similarities and differences between IL11 and IL11RA1 knockout mice for lung fibro-inflammation, fertility and craniosynostosis

par Benjamin Ng, Anissa A. Widjaja, Sivakumar Viswanathan, Jinrui Dong, Sonia P. Chothani, Stella Lim, Shamini G. Shekeran, Jessie Tan, Narelle E. McGregor, Emma C. Walker, Natalie A. Sims, Sebastian Schafer, Stuart A. Cook
Publié 2021

Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH

par Jinrui Dong, Sivakumar Viswanathan, Eleonora Adami, Brijesh K. Singh, Sonia P. Chothani, Benjamin Ng, Wei Wen Lim, Jin Zhou, Madhulika Tripathi, Nicole S. J. Ko, Shamini G. Shekeran, Jessie Tan, Sze Yun Lim, Mao Wang, Pei Min Lio, Paul M. Yen, Sebastian Schafer, Stuart A. Cook, Anissa A. Widjaja
Publié 2021