Micro-pharmacokinetics: Quantifying local drug concentration at live cell membranes

por Karolina Gherbi, Stephen J. Briddon, Steven J. Charlton
Publicado 2018

Reply to ‘Antipsychotics with similar association kinetics at dopamine D2 receptors differ in extrapyramidal side-effects’

por David A. Sykes, J. Robert Lane, Monika Szabo, Ben Capuano, Jonathan A. Javitch, Steven J. Charlton
Publicado 2018

Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D2 receptors

por David A. Sykes, Holly Moore, Lisa Stott, Nicholas Holliday, Jonathan A. Javitch, J. Robert Lane, Steven J. Charlton
Publicado 2017

The role of kinetic context in apparent biased agonism at GPCRs

por Carmen Klein Herenbrink, David A. Sykes, Prashant Donthamsetti, Meritxell Canals, Thomas Coudrat, Jeremy Shonberg, Peter J. Scammells, Ben Capuano, Patrick M. Sexton, Steven J. Charlton, Jonathan A. Javitch, Arthur Christopoulos, J. Robert Lane
Publicado 2016