Large enhancement of response times of a protein conformational switch by computational design

por Alex J. DeGrave, Jeung-Hoi Ha, Stewart N. Loh, Lillian T. Chong
Publicado 2018

The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding

por Mark R. Woodford, Diana M. Dunn, Adam R. Blanden, Dante Capriotti, David Loiselle, Chrisostomos Prodromou, Barry Panaretou, Philip F. Hughes, Aaron Smith, Wendi Ackerman, Timothy A. Haystead, Stewart N. Loh, Dimitra Bourboulia, Laura S. Schmidt, W. Marston Linehan, Gennady Bratslavsky, Mehdi Mollapour
Publicado 2016

EGCG binds intrinsically disordered N-terminal domain of p53 and disrupts p53-MDM2 interaction

por Jing Zhao, Alan Blayney, Xiaorong Liu, Lauren Gandy, Weihua Jin, Lufeng Yan, Jeung-Hoi Ha, Ashley J. Canning, Michael Connelly, Chao Yang, Xinyue Liu, Yuanyuan Xiao, Michael S. Cosgrove, Sozanne R. Solmaz, Yingkai Zhang, David Ban, Jianhan Chen, Stewart N. Loh, Chunyu Wang
Publicado 2021