ChAdOx1-vectored Lassa fever vaccine elicits a robust cellular and humoral immune response and protects guinea pigs against lethal Lassa virus challenge

por Robert J. Fischer, Jyothi N. Purushotham, Neeltje van Doremalen, Sarah Sebastian, Kimberly Meade-White, Kathleen Cordova, Michael Letko, M. Jeremiah Matson, Friederike Feldmann, Elaine Haddock, Rachel LaCasse, Greg Saturday, Teresa Lambe, Sarah C. Gilbert, Vincent J. Munster
Publicado 2021

A naturally protective epitope of limited variability as an influenza vaccine target

por Craig P. Thompson, José Lourenço, Adam A. Walters, Uri Obolski, Matthew Edmans, Duncan S. Palmer, Kreepa Kooblall, George W. Carnell, Daniel O’Connor, Thomas A. Bowden, Oliver G. Pybus, Andrew J. Pollard, Nigel J. Temperton, Teresa Lambe, Sarah C. Gilbert, Sunetra Gupta
Publicado 2018

Heterologous vaccination regimens with self-amplifying RNA and adenoviral COVID vaccines induce robust immune responses in mice

por Alexandra J. Spencer, Paul F. McKay, Sandra Belij-Rammerstorfer, Marta Ulaszewska, Cameron D. Bissett, Kai Hu, Karnyart Samnuan, Anna K. Blakney, Daniel Wright, Hannah R. Sharpe, Ciaran Gilbride, Adam Truby, Elizabeth R. Allen, Sarah C. Gilbert, Robin J. Shattock, Teresa Lambe
Publicado 2021

ChAdOx1 nCoV-19 (AZD1222) protects Syrian hamsters against SARS-CoV-2 B.1.351 and B.1.1.7

por Robert J. Fischer, Neeltje van Doremalen, Danielle R. Adney, Claude Kwe Yinda, Julia R. Port, Myndi G. Holbrook, Jonathan E. Schulz, Brandi N. Williamson, Tina Thomas, Kent Barbian, Sarah L. Anzick, Stacy Ricklefs, Brian J. Smith, Dan Long, Craig Martens, Greg Saturday, Emmie de Wit, Sarah C. Gilbert, Teresa Lambe, Vincent J. Munster
Publicado 2021

Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 lineages circulating in Brazil

por Sue Ann Costa Clemens, Pedro M. Folegatti, Katherine R. W. Emary, Lily Yin Weckx, Jeremy Ratcliff, Sagida Bibi, Ana Verena De Almeida Mendes, Eveline Pipolo Milan, Ana Pittella, Alexandre V. Schwarzbold, Eduardo Sprinz, Parvinder K. Aley, David Bonsall, Christophe Fraser, Michelle Fuskova, Sarah C. Gilbert, Daniel Jenkin, Sarah Kelly, Simon Kerridge, Teresa Lambe, Natalie G. Marchevsky, Yama F. Mujadidi, Emma Plested, Maheshi N. Ramasamy, Peter Simmonds, Tanya Golubchik, Merryn Voysey, Andrew J. Pollard, the AMPHEUS Project, Oxford COVID Vaccine Trial Team
Publicado 2021

Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya

por Ifedayo M. O. Adetifa, Sophie Uyoga, John N. Gitonga, Daisy Mugo, Mark Otiende, James Nyagwange, Henry K. Karanja, James Tuju, Perpetual Wanjiku, Rashid Aman, Mercy Mwangangi, Patrick Amoth, Kadondi Kasera, Wangari Ng’ang’a, Charles Rombo, Christine Yegon, Khamisi Kithi, Elizabeth Odhiambo, Thomas Rotich, Irene Orgut, Sammy Kihara, Christian Bottomley, Eunice W. Kagucia, Katherine E. Gallagher, Anthony Etyang, Shirine Voller, Teresa Lambe, Daniel Wright, Edwine Barasa, Benjamin Tsofa, Philip Bejon, Lynette I. Ochola-Oyier, Ambrose Agweyu, J. Anthony G. Scott, George M. Warimwe
Publicado 2021

ChAdOx1 nCoV-19 (AZD1222) vaccine candidate significantly reduces SARS-CoV-2 shedding in ferrets

por Glenn A. Marsh, Alexander J. McAuley, Gough G. Au, Sarah Riddell, Daniel Layton, Nagendrakumar B. Singanallur, Rachel Layton, Jean Payne, Peter A. Durr, Hannah Bender, Jennifer A. Barr, John Bingham, Victoria Boyd, Sheree Brown, Matthew P. Bruce, Kathie Burkett, Teresa Eastwood, Sarah Edwards, Tamara Gough, Kim Halpin, Jenni Harper, Clare Holmes, William S. J. Horman, Petrus Jansen van Vuren, Suzanne Lowther, Kate Maynard, Kristen D. McAuley, Matthew J. Neave, Timothy Poole, Christina Rootes, Brenton Rowe, Elisha Soldani, Vittoria Stevens, Cameron R. Stewart, Willy W. Suen, Mary Tachedjian, Shawn Todd, Lee Trinidad, Duane Walter, Naomi Watson, Trevor W. Drew, Sarah C. Gilbert, Teresa Lambe, S. S. Vasan
Publicado 2021

ChAdOx1 nCoV-19 protection against SARS-CoV-2 in rhesus macaque and ferret challenge models

por Teresa Lambe, Alexandra J. Spencer, Kelly M. Thomas, Karen E. Gooch, Stephen Thomas, Andrew D. White, Holly E. Humphries, Daniel Wright, Sandra Belij-Rammerstorfer, Nazia Thakur, Carina Conceicao, Robert Watson, Leonie Alden, Lauren Allen, Marilyn Aram, Kevin R. Bewley, Emily Brunt, Phillip Brown, Breeze E. Cavell, Rebecca Cobb, Susan A. Fotheringham, Ciaran Gilbride, Debbie J. Harris, Catherine M. K. Ho, Laura Hunter, Chelsea L. Kennard, Stephanie Leung, Vanessa Lucas, Didier Ngabo, Kathryn A. Ryan, Hannah Sharpe, Charlotte Sarfas, Laura Sibley, Gillian S. Slack, Marta Ulaszewska, Nadina Wand, Nathan R. Wiblin, Fergus V. Gleeson, Dalan Bailey, Sally Sharpe, Sue Charlton, Francisco J. Salguero, Miles W. Carroll, Sarah C. Gilbert
Publicado 2021

T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses

por Ane Ogbe, Barbara Kronsteiner, Donal T. Skelly, Matthew Pace, Anthony Brown, Emily Adland, Kareena Adair, Hossain Delowar Akhter, Mohammad Ali, Serat-E Ali, Adrienn Angyal, M. Azim Ansari, Carolina V. Arancibia-Cárcamo, Helen Brown, Senthil Chinnakannan, Christopher Conlon, Catherine de Lara, Thushan de Silva, Christina Dold, Tao Dong, Timothy Donnison, David Eyre, Amy Flaxman, Helen Fletcher, Joshua Gardner, James T. Grist, Carl-Philipp Hackstein, Kanoot Jaruthamsophon, Katie Jeffery, Teresa Lambe, Lian Lee, Wenqin Li, Nicholas Lim, Philippa C. Matthews, Alexander J. Mentzer, Shona C. Moore, Dean J. Naisbitt, Monday Ogese, Graham Ogg, Peter Openshaw, Munir Pirmohamed, Andrew J. Pollard, Narayan Ramamurthy, Patpong Rongkard, Sarah Rowland-Jones, Oliver Sampson, Gavin Screaton, Alessandro Sette, Lizzie Stafford, Craig Thompson, Paul J. Thomson, Ryan Thwaites, Vinicius Vieira, Daniela Weiskopf, Panagiota Zacharopoulou, Oxford Immunology Network Covid-19 Response T Cell Consortium, Oxford Protective T Cell Immunology for COVID-19 (OPTIC) Clinical Team, Lance Turtle, Paul Klenerman, Philip Goulder, John Frater, Eleanor Barnes, Susanna Dunachie
Publicado 2021