Engineering a vector-based pan-Leishmania vaccine for humans: proof of principle

par Pedro Cecílio, James Oristian, Claudio Meneses, Tiago D. Serafim, Jesus G. Valenzuela, Anabela Cordeiro da Silva, Fabiano Oliveira
Publié 2020

RNAi screening identifies Trypanosoma brucei stress response protein kinases required for survival in the mouse

par Fernando Fernandez-Cortes, Tiago D. Serafim, Jonathan M. Wilkes, Nathaniel G. Jones, Ryan Ritchie, Richard McCulloch, Jeremy C. Mottram
Publié 2017

Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei.

par Jennifer A Stortz, Tiago D Serafim, Sam Alsford, Jonathan Wilkes, Fernando Fernandez-Cortes, Graham Hamilton, Emma Briggs, Leandro Lemgruber, David Horn, Jeremy C Mottram, Richard McCulloch
Publié 2017

The Gut Microbiome of the Vector <italic toggle="yes">Lutzomyia longipalpis</italic> Is Essential for Survival of <italic toggle="yes">Leishmania infantum</italic>

par Patrick H. Kelly, Sarah M. Bahr, Tiago D. Serafim, Nadim J. Ajami, Joseph F. Petrosino, Claudio Meneses, John R. Kirby, Jesus G. Valenzuela, Shaden Kamhawi, Mary E. Wilson
Publié 2017

A sand fly salivary protein acts as a neutrophil chemoattractant

par Anderson B. Guimaraes-Costa, John P. Shannon, Ingrid Waclawiak, Jullyanna Oliveira, Claudio Meneses, Waldione de Castro, Xi Wen, Joseph Brzostowski, Tiago D. Serafim, John F. Andersen, Heather D. Hickman, Shaden Kamhawi, Jesus G. Valenzuela, Fabiano Oliveira
Publié 2021

A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain using CRISPR gene editing

par Wen-Wei Zhang, Subir Karmakar, Sreenivas Gannavaram, Ranadhir Dey, Patrick Lypaczewski, Nevien Ismail, Abid Siddiqui, Vahan Simonyan, Fabiano Oliveira, Iliano V. Coutinho-Abreu, Thiago DeSouza-Vieira, Claudio Meneses, James Oristian, Tiago D. Serafim, Abu Musa, Risa Nakamura, Noushin Saljoughian, Greta Volpedo, Monika Satoskar, Sanika Satoskar, Pradeep K. Dagur, J. Philip McCoy, Shaden Kamhawi, Jesus G. Valenzuela, Shinjiro Hamano, Abhay R. Satoskar, Greg Matlashewski, Hira L. Nakhasi
Publié 2020