Development of small molecule inhibitors targeting PBX1 transcription signaling as a novel cancer therapeutic strategy

por Yao-An Shen, Jin Jung, Geoffrey D. Shimberg, Fang-Chi Hsu, Yohan Suryo Rahmanto, Stephanie L. Gaillard, Jiaxin Hong, Jürgen Bosch, Ie-Ming Shih, Chi-Mu Chuang, Tian-Li Wang
Publicado 2021

Genomic characterization of genes encoding histone acetylation modulator proteins identifies therapeutic targets for cancer treatment

por Zhongyi Hu, Junzhi Zhou, Junjie Jiang, Jiao Yuan, Youyou Zhang, Xuepeng Wei, Nicki Loo, Yueying Wang, Yutian Pan, Tianli Zhang, Xiaomin Zhong, Meixiao Long, Kathleen T. Montone, Janos L. Tanyi, Yi Fan, Tian-Li Wang, Ie-Ming Shih, Xiaowen Hu, Lin Zhang
Publicado 2019

Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming

por Yohan Suryo Rahmanto, Wenjing Shen, Xu Shi, Xi Chen, Yu Yu, Zheng-Cheng Yu, Tsutomu Miyamoto, Meng-Horng Lee, Vivek Singh, Ryoichi Asaka, Geoffrey Shimberg, Michele I. Vitolo, Stuart S. Martin, Denis Wirtz, Ronny Drapkin, Jianhua Xuan, Tian-Li Wang, Ie-Ming Shih
Publicado 2020

High grade serous ovarian carcinomas originate in the fallopian tube

por S. Intidhar Labidi-Galy, Eniko Papp, Dorothy Hallberg, Noushin Niknafs, Vilmos Adleff, Michael Noe, Rohit Bhattacharya, Marian Novak, Siân Jones, Jillian Phallen, Carolyn A. Hruban, Michelle S. Hirsch, Douglas I. Lin, Lauren Schwartz, Cecile L. Maire, Jean-Christophe Tille, Michaela Bowden, Ayse Ayhan, Laura D. Wood, Robert B. Scharpf, Robert Kurman, Tian-Li Wang, Ie-Ming Shih, Rachel Karchin, Ronny Drapkin, Victor E. Velculescu
Publicado 2017