Pharmacological Poly (ADP-Ribose) Polymerase Inhibitors Decrease Mycobacterium tuberculosis Survival in Human Macrophages

por Cassandra L. R. van Doorn, Sanne A. M. Steenbergen, Kimberley V. Walburg, Tom H. M. Ottenhoff
Publicado 2021

In-vivo expressed Mycobacterium tuberculosis antigens recognised in three mouse strains after infection and BCG vaccination

por Mariateresa Coppola, Fabienne Jurion, Susan J. F. van den Eeden, Hermann Giresse Tima, Kees L. M. C. Franken, Annemieke Geluk, Marta Romano, Tom H. M. Ottenhoff
Publicado 2021

A high-throughput screen for tuberculosis progression.

por Ralph Carvalho, Jan de Sonneville, Oliver W Stockhammer, Nigel D L Savage, Wouter J Veneman, Tom H M Ottenhoff, Ron P Dirks, Annemarie H Meijer, Herman P Spaink
Publicado 2011

Novel transcriptional signatures for sputum-independent diagnostics of tuberculosis in children

por John Espen Gjøen, Synne Jenum, Dhanasekaran Sivakumaran, Aparna Mukherjee, Ragini Macaden, Sushil K. Kabra, Rakesh Lodha, Tom H. M. Ottenhoff, Marielle C. Haks, Timothy Mark Doherty, Christian Ritz, Harleen M. S. Grewal
Publicado 2017

Combined chemical genetics and data-driven bioinformatics approach identifies receptor tyrosine kinase inhibitors as host-directed antimicrobials

por Cornelis J. Korbee, Matthias T. Heemskerk, Dragi Kocev, Elisabeth van Strijen, Omid Rabiee, Kees L. M. C. Franken, Louis Wilson, Nigel D. L. Savage, Sašo Džeroski, Mariëlle C. Haks, Tom H. M. Ottenhoff
Publicado 2018

Metabolite changes in blood predict the onset of tuberculosis

por January Weiner, Jeroen Maertzdorf, Jayne S. Sutherland, Fergal J. Duffy, Ethan Thompson, Sara Suliman, Gayle McEwen, Bonnie Thiel, Shreemanta K. Parida, Joanna Zyla, Willem A. Hanekom, Robert P. Mohney, W. Henry Boom, Harriet Mayanja-Kizza, Rawleigh Howe, Hazel M. Dockrell, Tom H. M. Ottenhoff, Thomas J. Scriba, Daniel E. Zak, Gerhard Walzl, Stefan H. E. Kaufmann, The GC6-74 consortium
Publicado 2018