Shear-mediated sol-gel transition of regenerated silk allows the formation of Janus-like microgels

por Zenon Toprakcioglu, Tuomas P. J. Knowles
Publicado 2021

Connecting macroscopic observables and microscopic assembly events in amyloid formation using coarse grained simulations.

por Noah S Bieler, Tuomas P J Knowles, Daan Frenkel, Robert Vácha
Publicado 2012

Single molecule secondary structure determination of proteins through infrared absorption nanospectroscopy

por Francesco Simone Ruggeri, Benedetta Mannini, Roman Schmid, Michele Vendruscolo, Tuomas P. J. Knowles
Publicado 2020

Controlled self-assembly of plant proteins into high-performance multifunctional nanostructured films

por Ayaka Kamada, Marc Rodriguez-Garcia, Francesco Simone Ruggeri, Yi Shen, Aviad Levin, Tuomas P. J. Knowles
Publicado 2021

Infrared nanospectroscopy reveals the molecular interaction fingerprint of an aggregation inhibitor with single Aβ42 oligomers

por Francesco Simone Ruggeri, Johnny Habchi, Sean Chia, Robert I. Horne, Michele Vendruscolo, Tuomas P. J. Knowles
Publicado 2021

Fabrication of fibrillosomes from droplets stabilized by protein nanofibrils at all-aqueous interfaces

por Yang Song, Ulyana Shimanovich, Thomas C. T. Michaels, Qingming Ma, Jingmei Li, Tuomas P. J. Knowles, Ho Cheung Shum
Publicado 2016

Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils

por Yang Song, Thomas C. T. Michaels, Qingming Ma, Zhou Liu, Hao Yuan, Shuichi Takayama, Tuomas P. J. Knowles, Ho Cheung Shum
Publicado 2018

Dynamic microfluidic control of supramolecular peptide self-assembly

por Zohar A. Arnon, Andreas Vitalis, Aviad Levin, Thomas C. T. Michaels, Amedeo Caflisch, Tuomas P. J. Knowles, Lihi Adler-Abramovich, Ehud Gazit
Publicado 2016

Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity

por Francesco Simone Ruggeri, Jerome Charmet, Tadas Kartanas, Quentin Peter, Sean Chia, Johnny Habchi, Christopher M. Dobson, Michele Vendruscolo, Tuomas P. J. Knowles
Publicado 2018

Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation

por Paolo Arosio, Thomas C. T. Michaels, Sara Linse, Cecilia Månsson, Cecilia Emanuelsson, Jenny Presto, Jan Johansson, Michele Vendruscolo, Christopher M. Dobson, Tuomas P. J. Knowles
Publicado 2016

Screening of small molecules using the inhibition of oligomer formation in α-synuclein aggregation as a selection parameter

por Roxine Staats, Thomas C. T. Michaels, Patrick Flagmeier, Sean Chia, Robert I. Horne, Johnny Habchi, Sara Linse, Tuomas P. J. Knowles, Christopher M. Dobson, Michele Vendruscolo
Publicado 2020

Physical Determinants of Amyloid Assembly in Biofilm Formation

por Maria Andreasen, Georg Meisl, Jonathan D. Taylor, Thomas C. T. Michaels, Aviad Levin, Daniel E. Otzen, Matthew R. Chapman, Christopher M. Dobson, Steve J. Matthews, Tuomas P. J. Knowles
Publicado 2019

Silk micrococoons for protein stabilisation and molecular encapsulation

por Ulyana Shimanovich, Francesco S. Ruggeri, Erwin De Genst, Jozef Adamcik, Teresa P. Barros, David Porter, Thomas Müller, Raffaele Mezzenga, Christopher M. Dobson, Fritz Vollrath, Chris Holland, Tuomas P. J. Knowles
Publicado 2017

Publisher Correction: A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers

por Rodrigo Cataldi, Sean Chia, Katarina Pisani, Francesco S. Ruggeri, Catherine K. Xu, Tomas Šneideris, Michele Perni, Sunehera Sarwat, Priyanka Joshi, Janet R. Kumita, Sara Linse, Johnny Habchi, Tuomas P. J. Knowles, Benedetta Mannini, Christopher M. Dobson, Michele Vendruscolo
Publicado 2021

A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers

por Rodrigo Cataldi, Sean Chia, Katarina Pisani, Francesco S. Ruggeri, Catherine K. Xu, Tomas Šneideris, Michele Perni, Sunehera Sarwat, Priyanka Joshi, Janet R. Kumita, Sara Linse, Johnny Habchi, Tuomas P. J. Knowles, Benedetta Mannini, Christopher M. Dobson, Michele Vendruscolo
Publicado 2021

Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms

por Suman De, David C. Wirthensohn, Patrick Flagmeier, Craig Hughes, Francesco A. Aprile, Francesco S. Ruggeri, Daniel R. Whiten, Derya Emin, Zengjie Xia, Juan A. Varela, Pietro Sormanni, Franziska Kundel, Tuomas P. J. Knowles, Christopher M. Dobson, Clare Bryant, Michele Vendruscolo, David Klenerman
Publicado 2019

Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions

por Georg Krainer, Timothy J. Welsh, Jerelle A. Joseph, Jorge R. Espinosa, Sina Wittmann, Ella de Csilléry, Akshay Sridhar, Zenon Toprakcioglu, Giedre Gudiškytė, Magdalena A. Czekalska, William E. Arter, Jordina Guillén-Boixet, Titus M. Franzmann, Seema Qamar, Peter St George-Hyslop, Anthony A. Hyman, Rosana Collepardo-Guevara, Simon Alberti, Tuomas P. J. Knowles
Publicado 2021

Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes

por Ryan Limbocker, Sean Chia, Francesco S. Ruggeri, Michele Perni, Roberta Cascella, Gabriella T. Heller, Georg Meisl, Benedetta Mannini, Johnny Habchi, Thomas C. T. Michaels, Pavan K. Challa, Minkoo Ahn, Samuel T. Casford, Nilumi Fernando, Catherine K. Xu, Nina D. Kloss, Samuel I. A. Cohen, Janet R. Kumita, Cristina Cecchi, Michael Zasloff, Sara Linse, Tuomas P. J. Knowles, Fabrizio Chiti, Michele Vendruscolo, Christopher M. Dobson
Publicado 2019