Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis

por Lindsey Mayes-Hopfinger, Aura Enache, Jian Xie, Chou-Long Huang, Robert Köchl, Victor L. J. Tybulewicz, Teresa Fernandes-Alnemri, Emad S. Alnemri
Publicado 2021

Gene expression dysregulation domains are not a specific feature of Down syndrome

por Helena Ahlfors, Nneka Anyanwu, Edvinas Pakanavicius, Natalia Dinischiotu, Eva Lana-Elola, Sheona Watson-Scales, Justin Tosh, Frances Wiseman, James Briscoe, Karen Page, Elizabeth M. C. Fisher, Victor L. J. Tybulewicz
Publicado 2019

Publisher Correction: Genetic dissection of down syndrome‑associated alterations in APP/amyloid‑β biology using mouse models

por Justin L. Tosh, Elena R. Rhymes, Paige Mumford, Heather T. Whittaker, Laura J. Pulford, Sue J. Noy, Karen Cleverley, LonDownS Consortium, Matthew C. Walker, Victor L. J. Tybulewicz, Rob C. Wykes, Elizabeth M. C. Fisher, Frances K. Wiseman
Publicado 2021

Genetic dissection of down syndrome-associated alterations in APP/amyloid-β biology using mouse models

por Justin L. Tosh, Elena R. Rhymes, Paige Mumford, Heather T. Whittaker, Laura J. Pulford, Sue J. Noy, Karen Cleverley, LonDownS Consortium, Matthew C. Walker, Victor L. J. Tybulewicz, Rob C. Wykes, Elizabeth M. C. Fisher, Frances K. Wiseman
Publicado 2021

Maternal iron deficiency perturbs embryonic cardiovascular development in mice

por Jacinta I. Kalisch-Smith, Nikita Ved, Dorota Szumska, Jacob Munro, Michael Troup, Shelley E. Harris, Helena Rodriguez-Caro, Aimée Jacquemot, Jack J. Miller, Eleanor M. Stuart, Magda Wolna, Emily Hardman, Fabrice Prin, Eva Lana-Elola, Rifdat Aoidi, Elizabeth M. C. Fisher, Victor L. J. Tybulewicz, Timothy J. Mohun, Samira Lakhal-Littleton, Sarah De Val, Eleni Giannoulatou, Duncan B. Sparrow
Publicado 2021