Transketolase regulates sensitivity to APR-246 in p53-null cells independently of oxidative stress modulation

por Julia V. Milne, Bonnie Z. Zhang, Kenji M. Fujihara, Swati Dawar, Wayne A. Phillips, Nicholas J. Clemons
Publicado 2021

Physiological levels of Pik3ca(H1047R) mutation in the mouse mammary gland results in ductal hyperplasia and formation of ERα-positive tumors.

por Anjali Tikoo, Vincent Roh, Karen G Montgomery, Ivan Ivetac, Paul Waring, Rebecca Pelzer, Lauren Hare, Mark Shackleton, Patrick Humbert, Wayne A Phillips
Publicado 2012

Inhibiting the system xC−/glutathione axis selectively targets cancers with mutant-p53 accumulation

por David S. Liu, Cuong P. Duong, Sue Haupt, Karen G. Montgomery, Colin M. House, Walid J. Azar, Helen B. Pearson, Oliver M. Fisher, Matthew Read, Glen R. Guerra, Ygal Haupt, Carleen Cullinane, Klas G. Wiman, Lars Abrahmsen, Wayne A. Phillips, Nicholas J. Clemons
Publicado 2017

HOXA13 in etiology and oncogenic potential of Barrett’s esophagus

por Vincent T. Janmaat, Kateryna Nesteruk, Manon C. W. Spaander, Auke P. Verhaar, Bingting Yu, Rodrigo A. Silva, Wayne A. Phillips, Marcin Magierowski, Anouk van de Winkel, H. Scott Stadler, Tatiana Sandoval-Guzmán, Luc J. W. van der Laan, Ernst J. Kuipers, Ron Smits, Marco J. Bruno, Gwenny M. Fuhler, Nicholas J. Clemons, Maikel P. Peppelenbosch
Publicado 2021

Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling

por Inma M. Berenjeno, Roberto Piñeiro, Sandra D. Castillo, Wayne Pearce, Nicholas McGranahan, Sally M. Dewhurst, Valerie Meniel, Nicolai J. Birkbak, Evelyn Lau, Laurent Sansregret, Daniele Morelli, Nnennaya Kanu, Shankar Srinivas, Mariona Graupera, Victoria E. R. Parker, Karen G. Montgomery, Larissa S. Moniz, Cheryl L. Scudamore, Wayne A. Phillips, Robert K. Semple, Alan Clarke, Charles Swanton, Bart Vanhaesebroeck
Publicado 2017