Mosaic Drug Efflux Gene Sequences from Commensal <italic toggle="yes">Neisseria</italic> Can Lead to Low-Level Azithromycin Resistance Expressed by <italic toggle="yes">Neisseria g...

por William M. Shafer
Publicado 2018

Taking the Gonococcus-Human Relationship to a Whole New Level: Implications for the Coevolution of Microbes and Humans

por William M. Shafer, Elizabeth A. Ohneck
Publicado 2011

Dueling Regulatory Properties of a Transcriptional Activator (MtrA) and Repressor (MtrR) That Control Efflux Pump Gene Expression in <named-content content-type="genus-species">Nei...

por Yaramah M. Zalucki, Vijaya Dhulipala, William M. Shafer
Publicado 2012

Could Dampening Expression of the <named-content content-type="genus-species">Neisseria gonorrhoeae</named-content> <italic toggle="yes">mtrCDE</italic>-Encoded Efflux Pump Be a St...

por Shaochun Chen, Kristie L. Connolly, Corinne Rouquette-Loughlin, Alexander D’Andrea, Ann E. Jerse, William M. Shafer
Publicado 2019

A Novel Mechanism of High-Level, Broad-Spectrum Antibiotic Resistance Caused by a Single Base Pair Change in <named-content content-type="genus-species">Neisseria gonorrhoeae</name...

por Elizabeth A. Ohneck, Yaramah M. Zalucki, Paul J. T. Johnson, Vijaya Dhulipala, Daniel Golparian, Magnus Unemo, Ann E. Jerse, William M. Shafer
Publicado 2011

Cryo-EM Structures of a Gonococcal Multidrug Efflux Pump Illuminate a Mechanism of Drug Recognition and Resistance

por Meinan Lyu, Mitchell A. Moseng, Jennifer L. Reimche, Concerta L. Holley, Vijaya Dhulipala, Chih-Chia Su, William M. Shafer, Edward W. Yu
Publicado 2020

Control of <italic toggle="yes">gdhR</italic> Expression in <italic toggle="yes">Neisseria gonorrhoeae</italic> via Autoregulation and a Master Repressor (MtrR) of a Drug Efflux Pu...

por Corinne E. Rouquette-Loughlin, Yaramah M. Zalucki, Vijaya L. Dhulipala, Jacqueline T. Balthazar, Raúl G. Doyle, Robert A. Nicholas, Afrin A. Begum, Erica L. Raterman, Ann E. Jerse, William M. Shafer
Publicado 2017

Lipid A’s Structure Mediates <named-content content-type="genus-species">Neisseria gonorrhoeae</named-content> Fitness during Experimental Infection of Mice and Men

por Marcia M. Hobbs, James E. Anderson, Jacqueline T. Balthazar, Justin L. Kandler, Russell W. Carlson, Jhuma Ganguly, Afrin A. Begum, Joseph A. Duncan, Jessica T. Lin, P. Frederick Sparling, Ann E. Jerse, William M. Shafer
Publicado 2013

Mechanistic Basis for Decreased Antimicrobial Susceptibility in a Clinical Isolate of <named-content content-type="genus-species">Neisseria gonorrhoeae</named-content> Possessing a...

por Corinne E. Rouquette-Loughlin, Jennifer L. Reimche, Jacqueline T. Balthazar, Vijaya Dhulipala, Kim M. Gernert, Ellen N. Kersh, Cau D. Pham, Kevin Pettus, A. Jeanine Abrams, David L. Trees, Sancta St Cyr, William M. Shafer
Publicado 2018