The congenital cataract-linked A2V mutation impairs tetramer formation and promotes aggregation of βB2-crystallin.

por Jia Xu, Sha Wang, Wei-Jie Zhao, Yi-Bo Xi, Yong-Bin Yan, Ke Yao
Publicado 2012

The congenital cataract-linked G61C mutation destabilizes γD-crystallin and promotes non-native aggregation.

por Wang Zhang, Hong-Chen Cai, Fei-Feng Li, Yi-Bo Xi, Xu Ma, Yong-Bin Yan
Publicado 2011

Modeling congenital cataract in vitro using patient-specific induced pluripotent stem cells

por Danni Lyu, Lifang Zhang, Zhenwei Qin, Shuang Ni, Jiayong Li, Bing Lu, Shengjie Hao, Qiaomei Tang, Houfa Yin, Zhijian Chen, Yong-Bin Yan, Junfeng Ji, Jiliang He, Andras Nagy, Qiuli Fu, Ke Yao
Publicado 2021