Mining of the pyrrolamide antibiotics analogs in Streptomyces netropsis reveals the amidohydrolase-dependent "iterative strategy" underlying the pyrrole polymerization.

por Chunlin Hao, Sheng Huang, Zixin Deng, Changming Zhao, Yi Yu
Publicado 2014

<italic toggle="yes">In Vitro</italic> CRISPR/Cas9 System for Efficient Targeted DNA Editing

por Yunkun Liu, Weixin Tao, Shishi Wen, Zhengyuan Li, Anna Yang, Zixin Deng, Yuhui Sun
Publicado 2015

A novel target of IscS in Escherichia coli: participating in DNA phosphorothioation.

por Xianhui An, Wei Xiong, Yan Yang, Fuhou Li, Xiufen Zhou, Zhijun Wang, Zixin Deng, Jingdan Liang
Publicado 2012

Phosphorothioate-DNA bacterial diet reduces the ROS levels in C. elegans while improving locomotion and longevity

por Qiang Huang, Ruohan Li, Tao Yi, Fengsong Cong, Dayong Wang, Zixin Deng, Yi-Lei Zhao
Publicado 2021

Determination of the Protein-Protein Interactions within Acyl Carrier Protein (MmcB)-Dependent Modifications in the Biosynthesis of Mitomycin

por Dongjin Leng, Yong Sheng, Hengyu Wang, Jianhua Wei, Yixin Ou, Zixin Deng, Linquan Bai, Qianjin Kang
Publicado 2021

Offloading Role of a Discrete Thioesterase in Type II Polyketide Biosynthesis

por Kangmin Hua, Xiangyang Liu, Yuchun Zhao, Yaojie Gao, Lifeng Pan, Haoran Zhang, Zixin Deng, Ming Jiang
Publicado 2020

Regulatory Mechanism of Nicotine Degradation in <italic toggle="yes">Pseudomonas putida</italic>

por Haiyang Hu, Lijuan Wang, Weiwei Wang, Geng Wu, Fei Tao, Ping Xu, Zixin Deng, Hongzhi Tang
Publicado 2019

A severe leakage of intermediates to shunt products in acarbose biosynthesis

por Qinqin Zhao, Yuchang Luo, Xin Zhang, Qianjin Kang, Dan Zhang, Lili Zhang, Linquan Bai, Zixin Deng
Publicado 2020

Signature Arsenic Detoxification Pathways in <italic toggle="yes">Halomonas</italic> sp. Strain GFAJ-1

por Shuangju Wu, Lianrong Wang, Rui Gan, Tong Tong, Hao Bian, Zhiqiang Li, Shiming Du, Zixin Deng, Shi Chen
Publicado 2018

In vitro characterization of echinomycin biosynthesis: formation and hydroxylation of L-tryptophanyl-S-enzyme and oxidation of (2S,3S) β-hydroxytryptophan.

por Chen Zhang, Lingxin Kong, Qian Liu, Xuan Lei, Tao Zhu, Jun Yin, Birun Lin, Zixin Deng, Delin You
Publicado 2013

Improving the Precision of Base Editing by Bubble Hairpin Single Guide RNA

por Zhiwei Hu, Yannan Wang, Qian Liu, Yan Qiu, Zhiyu Zhong, Kangdi Li, Wenhua Li, Zixin Deng, Yuhui Sun
Publicado 2021

Structural basis for the biosynthesis of lovastatin

por Jialiang Wang, Jingdan Liang, Lu Chen, Wei Zhang, Liangliang Kong, Chao Peng, Chen Su, Yi Tang, Zixin Deng, Zhijun Wang
Publicado 2021

DNA Backbone Sulfur-Modification Expands Microbial Growth Range under Multiple Stresses by its anti-oxidation function

por Yan Yang, Guanpeng Xu, Jingdan Liang, Ying He, Lei Xiong, Hui Li, Douglas Bartlett, Zixin Deng, Zhijun Wang, Xiang Xiao
Publicado 2017

Molecular basis of regio- and stereo-specificity in biosynthesis of bacterial heterodimeric diketopiperazines

por Chenghai Sun, Zhenyao Luo, Wenlu Zhang, Wenya Tian, Haidong Peng, Zhi Lin, Zixin Deng, Bostjan Kobe, Xinying Jia, Xudong Qu
Publicado 2020

Uncovering the cytochrome P450-catalyzed methylenedioxy bridge formation in streptovaricins biosynthesis

por Guo Sun, Chaoqun Hu, Qing Mei, Minghe Luo, Xu Chen, Zhengyuan Li, Yuanzhen Liu, Zixin Deng, Zhengyu Zhang, Yuhui Sun
Publicado 2020

A biocatalytic hydroxylation-enabled unified approach to C19-hydroxylated steroids

por Junlin Wang, Yanan Zhang, Huanhuan Liu, Yong Shang, Linjun Zhou, Penglin Wei, Wen-Bing Yin, Zixin Deng, Xudong Qu, Qianghui Zhou
Publicado 2019

Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system

por Le Yu, Wenting Zhou, Yixuan She, Hongmin Ma, You-Sheng Cai, Ming Jiang, Zixin Deng, Neil P. J. Price, Wenqing Chen
Publicado 2021

Structural basis for the recognition of sulfur in phosphorothioated DNA

por Guang Liu, Wencheng Fu, Zhenyi Zhang, Yao He, Hao Yu, Yuli Wang, Xiaolei Wang, Yi-Lei Zhao, Zixin Deng, Geng Wu, Xinyi He
Publicado 2018

A new type of DNA phosphorothioation-based antiviral system in archaea

por Lei Xiong, Siyi Liu, Si Chen, Yao Xiao, Bochen Zhu, Yali Gao, Yujing Zhang, Beibei Chen, Jie Luo, Zixin Deng, Xiangdong Chen, Lianrong Wang, Shi Chen
Publicado 2019

SspABCD-SspFGH Constitutes a New Type of DNA Phosphorothioate-Based Bacterial Defense System

por Shiwei Wang, Mengping Wan, Ruolin Huang, Yujing Zhang, Yuqing Xie, Yue Wei, Mustafa Ahmad, Dan Wu, Yue Hong, Zixin Deng, Shi Chen, Zhiqiang Li, Lianrong Wang
Publicado 2021