FK866 attenuates acute hepatic failure through c-jun-N-terminal kinase (JNK)-dependent autophagy
Abstract FK866 exhibits a protective effect on D-galactosamine (GaIN)/lipopolysaccharide (LPS) and concanavalin A (ConA)-induced acute liver failure (ALF), but the mechanism by which FK866 affords this benefit has not yet been elucidated. Autophagy has a protective effect on acute liver injury. Howe...
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Autores principales: | , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2017
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Acceso en línea: | https://doaj.org/article/000477d9d4174f0b8016ec4b3ee915b7 |
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