CMV latent infection improves CD8+ T response to SEB due to expansion of polyfunctional CD57+ cells in young individuals.

Cytomegalovirus (CMV) latent infection has a deleterious effect on the efficacy of influenza vaccination in the elderly, suggesting that CMV restricts immunological diversity impairing the immune system functionality in old age. Polyfunctional T cells produce multiple cytokines and higher amounts th...

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Autores principales: Alejandra Pera, Carmen Campos, Alonso Corona, Beatriz Sanchez-Correa, Raquel Tarazona, Anis Larbi, Rafael Solana
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/0056beed74f948f5919bb8f1c4dfd638
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