Targeted therapy for LIMD1-deficient non-small cell lung cancer subtypes
Abstract An early event in lung oncogenesis is loss of the tumour suppressor gene LIMD1 (LIM domains containing 1); this encodes a scaffold protein, which suppresses tumorigenesis via a number of different mechanisms. Approximately 45% of non-small cell lung cancers (NSCLC) are deficient in LIMD1, y...
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Autores principales: | , , , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Publishing Group
2021
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Acceso en línea: | https://doaj.org/article/006a5cc989ef440e83fa93a4ded65708 |
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