A novel CD34-derived hinge for rapid and efficient detection and enrichment of CAR T cells

Immunotherapy including chimeric antigen receptor (CAR) T cell therapy has revolutionized modern cancer therapy and has achieved remarkable remission and survival rates for several malignancies with historically dismal outcomes. The hinge of the CAR connects the antigen binding to the transmembrane...

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Bibliographic Details
Main Authors: Arthur Bister, Tabea Ibach, Corinna Haist, Denise Smorra, Katharina Roellecke, Martin Wagenmann, Kathrin Scheckenbach, Norbert Gattermann, Constanze Wiek, Helmut Hanenberg
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
CAR
Online Access:https://doaj.org/article/00a59fbab47c466695dfcb76861adbf7
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