Identification and characterization of CDH1 germline variants in sporadic gastric cancer patients and in individuals at risk of gastric cancer.

Identification and characterization of CDH1 germline variants in sporadic gastric cancer patients and in individuals at risk of gastric cancer.

<h4>Objective</h4>To screen and characterize germline variants for E-cadherin (CDH1) in non-hereditary gastric cancer (GC) patients and in subjects at risk of GC.<h4>Methods</h4>59 GCs, 59 first degree relatives (FDRs) of GC, 20 autoimmune metaplastic atrophic gastritis (AMAG...

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Auteurs principaux: Marica Garziera, Vincenzo Canzonieri, Renato Cannizzaro, Silvano Geremia, Laura Caggiari, Mariangela De Zorzi, Stefania Maiero, Enrico Orzes, Tiziana Perin, Stefania Zanussi, Paolo De Paoli, Valli De Re
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/00be5c83978740a68758cc14f936e463
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https://doaj.org/article/00be5c83978740a68758cc14f936e463

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