Reflectance confocal microscopy of an inverted follicular keratosis mimicking a squamous cell carcinoma

Distinguishing between benign and malignant neoplasms of the skin is a daily challenge to dermatologists. With the use of a dermatoscope and other imaging devices, the diagnosis is often more precise. The confocal microscope is a device that uses a near-infrared laser to perform noninvasive imaging...

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Bibliographic Details
Main Authors: Sarah Hocker, Harold S. Rabinovitz, Margaret Oliveiro, Jane Grant-Kels, Alon Scope
Format: article
Language:EN
Published: Mattioli1885 2017
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Online Access:https://doaj.org/article/00bebe0c0b9a49f6acb6ae8429bab81a
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Summary:Distinguishing between benign and malignant neoplasms of the skin is a daily challenge to dermatologists. With the use of a dermatoscope and other imaging devices, the diagnosis is often more precise. The confocal microscope is a device that uses a near-infrared laser to perform noninvasive imaging of the skin. The benefit is that the images immediately provide additional, cellular-level information that can assist in diagnosis. However, lesions may share overlapping characteristics on confocal microscopy, and hence, benign lesions can still display confocal features concerning for a cancerous process, justifying a biopsy. Here, we present a case of an inverted follicular keratosis imitating a squamous cell carcinoma on confocal microscopy.