Real-time visualization of conformational changes within single MloK1 cyclic nucleotide-modulated channels
Some ion channels are modulated by binding of cyclic nucleotide to a cyclic nucleotide-binding domain. Here, the authors use high-speed atomic force microscopy to directly monitor the conformational changes induced by ligand binding to a cyclic nucleotide-modulated channel from Mesorhizobium loti.
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Auteurs principaux: | Martina Rangl, Atsushi Miyagi, Julia Kowal, Henning Stahlberg, Crina M. Nimigean, Simon Scheuring |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2016
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Sujets: | |
Accès en ligne: | https://doaj.org/article/00cdeb3d89d7440fa91c5c72fa6ce7e5 |
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