Single-cell transcriptome identifies molecular subtype of autism spectrum disorder impacted by de novo loss-of-function variants regulating glial cells

Abstract Background In recent years, several hundred autism spectrum disorder (ASD) implicated genes have been discovered impacting a wide range of molecular pathways. However, the molecular underpinning of ASD, particularly from the point of view of ‘brain to behaviour’ pathogenic mechanisms, remai...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Nasna Nassir, Asma Bankapur, Bisan Samara, Abdulrahman Ali, Awab Ahmed, Ibrahim M. Inuwa, Mehdi Zarrei, Seyed Ali Safizadeh Shabestari, Ammar AlBanna, Jennifer L. Howe, Bakhrom K. Berdiev, Stephen W. Scherer, Marc Woodbury-Smith, Mohammed Uddin
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Single-cell transcriptomics Autism spectrum disorder De novo LOF variant Glial cell type Brain tissue Medicine R Genetics QH426-470
Acceso en línea:	https://doaj.org/article/00dc4650ae5a4c8da8d8c168cea1f017
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Sea el primero en dejar un comentario!

Single-cell transcriptome identifies molecular subtype of autism spectrum disorder impacted by de novo loss-of-function variants regulating glial cells

Ejemplares similares