MiRNA-200C expression in Fanconi anemia pathway functionally deficient lung cancers

Abstract The Fanconi Anemia (FA) pathway is essential for human cells to maintain genomic integrity following DNA damage. This pathway is involved in repairing damaged DNA through homologous recombination. Cancers with a defective FA pathway are expected to be more sensitive to cross-link based ther...

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Auteurs principaux: Wenrui Duan, Shirley Tang, Li Gao, Kathleen Dotts, Andrew Fink, Arjun Kalvala, Brittany Aguila, Qi-En Wang, Miguel A. Villalona-Calero
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/00e5274edafd4aabbc69514504bfd27d
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