MiRNA-200C expression in Fanconi anemia pathway functionally deficient lung cancers

MiRNA-200C expression in Fanconi anemia pathway functionally deficient lung cancers

Abstract The Fanconi Anemia (FA) pathway is essential for human cells to maintain genomic integrity following DNA damage. This pathway is involved in repairing damaged DNA through homologous recombination. Cancers with a defective FA pathway are expected to be more sensitive to cross-link based ther...

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Autores principales: Wenrui Duan, Shirley Tang, Li Gao, Kathleen Dotts, Andrew Fink, Arjun Kalvala, Brittany Aguila, Qi-En Wang, Miguel A. Villalona-Calero
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/00e5274edafd4aabbc69514504bfd27d
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