Overactive autophagy is a pathological mechanism underlying premature suture ossification in nonsyndromic craniosynostosis

Abstract Nonsyndromic craniosynostosis (NSC) is the most common craniosynostosis with the primary defect being one or more fused sutures. In contrast to syndromic craniosynostosis, the etiopathogenesis of NSC is largely unknown. Here we show that autophagy, a major catabolic process required for the...

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Autores principales: Shanshan Qiu, Jing Wang, Siqi Huang, Shouqing Sun, Zhen Zhang, Nan Bao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/0103f64b043f49b086b6a5240d41b059
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