Electrostatic Forces Mediate the Specificity of RHO GTPase-GDI Interactions

Three decades of research have documented the spatiotemporal dynamics of RHO family GTPase membrane extraction regulated by guanine nucleotide dissociation inhibitors (GDIs), but the interplay of the kinetic mechanism and structural specificity of these interactions is as yet unresolved. To address...

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Auteurs principaux: Niloufar Mosaddeghzadeh, Neda S. Kazemein Jasemi, Jisca Majolée, Si-Cai Zhang, Peter L. Hordijk, Radovan Dvorsky, Mohammad Reza Ahmadian
Format: article
Langue:EN
Publié: MDPI AG 2021
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Accès en ligne:https://doaj.org/article/016abdbc02aa459eb551752890f5a0da
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