A Saccharomyces cerevisiae assay system to investigate ligand/AdipoR1 interactions that lead to cellular signaling.

Adiponectin is a mammalian hormone that exerts anti-diabetic, anti-cancer and cardioprotective effects through interaction with its major ubiquitously expressed plasma membrane localized receptors, AdipoR1 and AdipoR2. Here, we report a Saccharomyces cerevisiae based method for investigating agonist...

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Autores principales: Mustapha Aouida, Kangchang Kim, Abdul Rajjak Shaikh, Jose M Pardo, Jörg Eppinger, Dae-Jin Yun, Ray A Bressan, Meena L Narasimhan
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/0186600cc7d64a348ac6ad9fe6edce28
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