A Saccharomyces cerevisiae assay system to investigate ligand/AdipoR1 interactions that lead to cellular signaling.
Adiponectin is a mammalian hormone that exerts anti-diabetic, anti-cancer and cardioprotective effects through interaction with its major ubiquitously expressed plasma membrane localized receptors, AdipoR1 and AdipoR2. Here, we report a Saccharomyces cerevisiae based method for investigating agonist...
Guardado en:
Autores principales: | Mustapha Aouida, Kangchang Kim, Abdul Rajjak Shaikh, Jose M Pardo, Jörg Eppinger, Dae-Jin Yun, Ray A Bressan, Meena L Narasimhan |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/0186600cc7d64a348ac6ad9fe6edce28 |
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