Vaccine and Wild-Type Strains of Yellow Fever Virus Engage Distinct Entry Mechanisms and Differentially Stimulate Antiviral Immune Responses
ABSTRACT The live attenuated yellow fever virus (YFV) vaccine 17D stands as a “gold standard” for a successful vaccine. 17D was developed empirically by passaging the wild-type Asibi strain in mouse and chicken embryo tissues. Despite its immense success, the molecular determinants for virulence att...
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Main Authors: | , , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2016
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Online Access: | https://doaj.org/article/01c8d676a9da462694b2b0beecc6ea31 |
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