3D replicon distributions arise from stochastic initiation and domino-like DNA replication progression

DNA replication in higher eukaryotes is a complex process occurring in a complex genome environment. Here the authors present a model of DNA replication that incorporates random loop chromatin folding and domino-like fork progression reproducing the spatial and temporal characteristics of S-phase.

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Autores principales:	D. Löb, N. Lengert, V. O. Chagin, M. Reinhart, C. S. Casas-Delucchi, M. C. Cardoso, B. Drossel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/01dc71825b0b419da1a3f0217211fc56
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spelling	oai:doaj.org-article:01dc71825b0b419da1a3f0217211fc562021-12-02T16:50:15Z3D replicon distributions arise from stochastic initiation and domino-like DNA replication progression10.1038/ncomms112072041-1723https://doaj.org/article/01dc71825b0b419da1a3f0217211fc562016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11207https://doaj.org/toc/2041-1723DNA replication in higher eukaryotes is a complex process occurring in a complex genome environment. Here the authors present a model of DNA replication that incorporates random loop chromatin folding and domino-like fork progression reproducing the spatial and temporal characteristics of S-phase.D. LöbN. LengertV. O. ChaginM. ReinhartC. S. Casas-DelucchiM. C. CardosoB. DrosselNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q D. Löb N. Lengert V. O. Chagin M. Reinhart C. S. Casas-Delucchi M. C. Cardoso B. Drossel 3D replicon distributions arise from stochastic initiation and domino-like DNA replication progression
description	DNA replication in higher eukaryotes is a complex process occurring in a complex genome environment. Here the authors present a model of DNA replication that incorporates random loop chromatin folding and domino-like fork progression reproducing the spatial and temporal characteristics of S-phase.
format	article
author	D. Löb N. Lengert V. O. Chagin M. Reinhart C. S. Casas-Delucchi M. C. Cardoso B. Drossel
author_facet	D. Löb N. Lengert V. O. Chagin M. Reinhart C. S. Casas-Delucchi M. C. Cardoso B. Drossel
author_sort	D. Löb
title	3D replicon distributions arise from stochastic initiation and domino-like DNA replication progression
title_short	3D replicon distributions arise from stochastic initiation and domino-like DNA replication progression
title_full	3D replicon distributions arise from stochastic initiation and domino-like DNA replication progression
title_fullStr	3D replicon distributions arise from stochastic initiation and domino-like DNA replication progression
title_full_unstemmed	3D replicon distributions arise from stochastic initiation and domino-like DNA replication progression
title_sort	3d replicon distributions arise from stochastic initiation and domino-like dna replication progression
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/01dc71825b0b419da1a3f0217211fc56
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3D replicon distributions arise from stochastic initiation and domino-like DNA replication progression

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