Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain
Airah Javorsky et al. present the crystal structures of SARS-CoV-1 and SARS-CoV-2 E proteins in complex with the PALS1 PDZ domain. Their results suggest that the coronavirus E protein can interfere with normal PALS1 binding, potentially disrupting epithelial tissue integrity, and may provide future...
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Autores principales: | Airah Javorsky, Patrick O. Humbert, Marc Kvansakul |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/01e145d634fb42a783e337f538813dee |
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